Korean J Endocr Surg.  2012 Jun;12(2):112-114. 10.0000/kjes.2012.12.2.112.

Hyalinizing Trabecular Tumor of the Thyroid Gland

• Han SW
• Lee JH
• Woo HD
• Cho HD
• Song MS
• Kim SY
• Park NK

• KMID: 2375360
• DOI: http://doi.org/10.0000/kjes.2012.12.2.112

Abstract

A Hyalinizing Trabecular Tumor (HTT) is a very rare tumor. We report one case that was confirmed to be HTT after an operation. A 44-year-old female visited our hospital with about a 1.3-cm-sized mass on the left thyroid. Fine Needle Aspiration Biopsy (FNAB) indicated papillary thyroid cancer. After a left hemithyroidectomy, a frozen section biopsy reported the possibility of HTT. Therefore, we did not proceed with the surgery. According to the final report, she was diagnosed with HTT. Five lymph nodes were dissected and were found to be benign. Thyroid transcription factor-1 and neuron specific enolase were positive, and in addition calcitonin was negative. Ki-67 was recorded to be less than 5%. She was discharged without any complication. HTT is benign in most cases, but the possibility of malignancy should be considered. Because it is hard to differentiate between it and PTC or MTC, an accurate diagnosis through histologic examination of specimens and surgical resection is necessary.

Keyword

Hyalinizing trabecular tumor; Papillary thyroid cancer; Medullary thyroid cancer

MeSH Terms

Adult
Biopsy
Biopsy, Fine-Needle
Calcitonin
Diagnosis
Female
Frozen Sections
Humans
Hyalin*
Lymph Nodes
Phosphopyruvate Hydratase
Thyroid Gland*
Thyroid Neoplasms
Calcitonin
Phosphopyruvate Hydratase