J Korean Endocr Soc.  2009 Mar;24(1):54-57. 10.3803/jkes.2009.24.1.54.

A Case of Hyalinizing Trabecular Adenoma of the Thyroid Gland

• Shin HW
• Oh YL
• Jang HW
• Lee JI
• Kim SW
• Min YK
• Lee MS
• Lee MK
• Kim KW
• Chung JH

• KMID: 1468497
• DOI: http://doi.org/10.3803/jkes.2009.24.1.54

Abstract

Hyalinizing trabecular tumor is a rare benign thyroid tumor first described by Carney et al. in 1987. The tumor is characterized by an encapsulated nodule, trabecular arrangement of polygonal, oval, elongated cells, and hyalinized stroma. It is easily confused with papillary thyroid carcinoma or medullary thyroid carcinoma on surgical and cytologic specimens. A 45-year-old man presented with an incidentally detected left thyroid mass. Fine needle aspiration was performed and papillary thyroid carcinoma was suspected. However, the surgical specimen revealed a hyalinizing trabecular adenoma. We present this hyalinizing trabecular adenoma case to share our experience with physicians and specialists.

Keyword

hyalinizing trabecular tumor; thyroid gland; thyroid neoplasm

MeSH Terms

Adenoma
Biopsy, Fine-Needle
Carcinoma
Humans
Hyalin
Middle Aged
Specialization
Thyroid Gland
Thyroid Neoplasms
Carcinoma
Thyroid Neoplasms

Figure

• 

  Fig. 1 Thyroid ultrasonography. Ultrasonographic evaluation shows 0.8 × 0.5 cm indeterminate nodule (A) and small cyst adjacent to the nodule (B) in posterior aspect of left thyroid gland.

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  Fig. 2 Fine needle aspiration and cytology finding. Variable-sized nucleus with intranuclear pseudo-inclusions (indicated with arrow) are noted (H&E stain, ×400).

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  Fig. 3 Histologic finding. Tumor cells are arranged in trabecular pattern separated by stroma (H&E stain, ×200).

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