Arch Craniofac Surg.  2017 Mar;18(1):21-24. 10.7181/acfs.2017.18.1.21.

The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients

• Yang CE
• Park EK
• Lee MC
• Shim KW
• Kim YO

• KMID: 2375217
• DOI: http://doi.org/10.7181/acfs.2017.18.1.21

Abstract

BACKGROUND
In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study.
METHODS
Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull.
RESULTS
Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them.
CONCLUSION
PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan.

Keyword

Craniosynostosis; Positron emission tomography computed tomography; Evaluation

MeSH Terms

Brain
Craniosynostoses*
Electrons*
Glucose
Humans
Magnetic Resonance Imaging
Metabolism
Osteogenesis, Distraction
Positron-Emission Tomography*
Skull
Tomography, X-Ray Computed
Glucose