J Korean Med Sci.  2016 Aug;31(8):1279-1283. 10.3346/jkms.2016.31.8.1279.

Effects of High-Intensity-Focused Ultrasound Treatment on Benign Uterine Tumor

• Park J
• Lee JS
• Cho JH
• Kim S

• KMID: 2373757
• DOI: http://doi.org/10.3346/jkms.2016.31.8.1279

Abstract

In this study, the effects of high-intensity-focused ultrasound (HIFU) treatment on benign uterine tumor patients were examined. A total of 333 patients diagnosed with fibroids or adenomyosis using diagnostic sonography, treated with HIFU between February 4, 2010 and December 29, 2014 at a hospital in Korea, and followed up for three or six months were selected for this study. Their benign uterine tumor volume was measured, and the effects of HIFU treatment on the volume were analyzed according to age, disease, fertility, and treatment duration. The volume of benign tumors of the uterus changed by age in all age groups after conducting HIFU treatment for 3 and 6 months, respectively. The rate of decrease in individuals' in their twenties was the largest, at 64.9%. When the decreasing volume of benign tumors of the uterus was analyzed by type of disease, the treatment efficacy for adenomyosis was the best, with a decrease of 164.83 cm3 after 6 months. Myoma had the fastest decreasing rate, at 68.5%. When evaluated on the basis of fertility, the volume of benign tumors of the uterus continued to decrease until 6 months after completing all procedures. The volume has continued to decrease for 6 months after all procedures. This study showed that HIFU treatments for uterine fibroid and adenomyosis is an effective non-invasive therapy via reducing the benign uterine tumor volume. Therefore, the HIFU method might replace other conventional treatment methods.

Keyword

High-Intensity-Focused Ultrasound; Benign Uterine Tumor; Treatment Effects

MeSH Terms

Adenomyosis/diagnostic imaging
Adult
Female
Humans
Leiomyoma/diagnostic imaging
Middle Aged
Treatment Outcome
*Ultrasonic Therapy
Uterine Neoplasms/physiopathology/*radiotherapy
Uterus/physiopathology

Figure

• 

  Fig. 1 Measurement of the adenomyosis by ultrasound scanning. (A) Horizontal & vertical length. (B) Longitudinal length. (C) Horizontal and vertical length. (D) Longitudinal length.

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