Ann Lab Med.  2016 Mar;36(2):174-176. 10.3343/alm.2016.36.2.174.

Clinical Relevance of p53 Immunohistochemical Stain in the Differential Diagnosis Between Pediatric Aplastic Anemia and Refractory Cytopenia of Childhood

• Park SH
• Chi HS
• Cho YU
• Jang S
• Park CJ
• Im HJ
• Seo JJ

• KMID: 2373519
• DOI: http://doi.org/10.3343/alm.2016.36.2.174

Abstract

No abstract available.

MeSH Terms

Adolescent
Anemia, Aplastic/*diagnosis/pathology
Bone Marrow/pathology
Child
Child, Preschool
Diagnosis, Differential
Female
Half-Life
Humans
Immunohistochemistry
Male
Mutation
Myelodysplastic Syndromes/*diagnosis/pathology
Retrospective Studies
Tumor Suppressor Protein p53/genetics/*metabolism
Tumor Suppressor Protein p53

Figure

• 

  Fig. 1 Comparison example of the bone marrow aspirates (A and B, Wright stain, ×200 and ×1,000, respectively), biopsies (C and D, Hematoxylin & Eosin stain, ×100 and ×400, respectively), and p53 immunohistochemical (IHC) stain results (E and F, ×400) between the patient with pediatric aplastic anemia (A, C, and E) and possible refractory cytopenia of childhood (B, D, and F).

Reference

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