J Gastric Cancer.  2016 Mar;16(1):14-20. 10.5230/jgc.2016.16.1.14.

Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer: Is It a Safe Procedure in Countries with Non-Endemic Gastric Cancer Levels? A Preliminary Experience

• Bravo Neto GP
• Dos Santos EG
• Victer FC
• Neves MS
• Pinto MF
• Carvalho C

• KMID: 2372548
• DOI: http://doi.org/10.5230/jgc.2016.16.1.14

Abstract

PURPOSE
Early diagnosis of gastric cancer is still the exception in Western countries. In the East, as in Japan and Korea, this disease is an endemic disorder. More conservative surgical procedures are frequently performed in early gastric cancer cases in these countries where sentinel lymph node navigation surgery is becoming a safe option for some patients. This study aims to evaluate preliminary outcomes of patients with early gastric cancer who underwent sentinel node navigation surgeries in Brazil, a country with non-endemic gastric cancer levels.
MATERIALS AND METHODS
From September 2008 to March 2014, 14 out of 205 gastric cancer patients underwent sentinel lymph node navigation surgeries, which were performed using intraoperative, endoscopic, and peritumoral injection of patent blue dye.
RESULTS
Antrectomies with Billroth I gastroduodenostomies were performed in seven patients with distal tumors. The other seven patients underwent wedge resections. Sentinel basin resections were performed in four patients, and lymphadenectomies were extended to stations 7, 8, and 9 in the other 10. Two patients received false-negative results from sentinel node biopsies, and one of those patients had micrometastasis. There was one postoperative death from liver failure in a cirrhotic patient. Another cirrhotic patient died after two years without recurrence of gastric cancer, also from liver failure. All other patients were followed-up for 13 to 79 months with no evidence of recurrence.
CONCLUSIONS
Sentinel lymph node navigation surgery appears to be a safe procedure in a country with non-endemic levels of gastric cancer.

Keyword

Sentinel lymph node biopsy; Stomach neoplasms; Gastrectomy; Lymphadenectomy; Neoplasm micrometastasis

MeSH Terms

Biopsy
Brazil
Early Diagnosis
Gastrectomy
Gastroenterostomy
Humans
Japan
Korea
Liver Failure
Lymph Node Excision
Lymph Nodes*
Neoplasm Micrometastasis
Recurrence
Sentinel Lymph Node Biopsy
Stomach Neoplasms*

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