J Gastric Cancer.  2014 Jun;14(2):135-137.

Gastric Adenocarcinoma with Prostatic Metastasis

Affiliations
  • 1Department of Radiation Oncology, Regional Cancer Centre, Thiruvananthapuram, India.
  • 2Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, India. dranooptm@yahoo.co.in
  • 3Department of Pathology, Regional Cancer Centre, Thiruvananthapuram, India.
  • 4Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, India.

Abstract

Metastasis of gastric adenocarcinoma to the prostate gland is extremely rare. Herein, we report a case of gastric adenocarcinoma in a 56-year-old man with prostatic metastasis diagnosed through the analysis of biopsy specimens from representative lesions in the stomach and prostate gland. Immunohistochemistry of the prostatic tissue showed positive staining for cytokeratin 7 and negative staining for prostate-specific antigen (PSA), whereas the serum PSA level was normal, confirming the diagnosis of prostatic metastasis from carcinoma of the stomach.

Keyword

Stomach neoplasms; Adenocarcinoma; Prostatic secondaries

MeSH Terms

Adenocarcinoma*
Biopsy
Diagnosis
Humans
Immunohistochemistry
Keratin-7
Middle Aged
Negative Staining
Neoplasm Metastasis*
Prostate
Prostate-Specific Antigen
Stomach
Stomach Neoplasms
Keratin-7
Prostate-Specific Antigen

Reference

1. Zhang P, Zheng Y, Ran H, Leng Z, Wang Z. Case report: gastric adenocarcinoma metastatic to the prostate gland. J Radiol Case Rep. 2010; 4:35–38.
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2. Borum ML, Chen HC. Gastric adenocarcinoma metastatic to the prostate gland: a rare case and review of the literature. Dig Dis Sci. 2001; 46:2658–2659.
3. Bates AW, Baithun SI. Secondary solid neoplasms of the prostate: a clinico-pathological series of 51 cases. Virchows Arch. 2002; 440:392–396.
Article
4. Epstein JI. PSA and PAP as immunohistochemical markers in prostate cancer. Urol Clin North Am. 1993; 20:757–770.
Article
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