Psychiatry Investig.  2017 Mar;14(2):193-197. 10.4306/pi.2017.14.2.193.

Spectral Analysis of Polysomnography in Narcolepsy

• Yun SH
• Choi HD
• Seo WS

• KMID: 2371800
• DOI: http://doi.org/10.4306/pi.2017.14.2.193

Abstract

OBJECTIVE
This study was conducted to identify differences between people with narcolepsy and the normal control of delta and theta activity using electroencephalogram (EEG) spectrum analysis of nocturnal polysomnography (PSG).
METHODS
Seven narcolepsy patients and seven age-sex matched normal controls underwent PSG and multiple sleep latency tests. Participants' non-rapid eye movement (NREM) sleep EEGs in PSG was analyzed using a Fast Fourier Transform technique.
RESULTS
While NREM delta activity of people with narcolepsy declined during the first three periods of NREM, there was no change during the 4th period of NREM. The increase in NREM theta activity also lasted until the 3rd period of NREM but did not occur during the 4th period of NREM. In comparing sleep parameters, REM sleep latency in the narcolepsy group was significantly shorter than in controls.
CONCLUSION
These results suggest that people with narcolepsy are likely to have a delta and theta activity-related sleep disturbance mechanism in NREM sleep.

Keyword

Narcolepsy; Delta activity; Theta activity; Electroencephalogram; Spectral analysis

MeSH Terms

Electroencephalography
Eye Movements
Fourier Analysis
Humans
Narcolepsy*
Polysomnography*
Sleep, REM
Spectrum Analysis