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Recent Updates on Narcolepsy and Hypersomnia

Hong S

Narcolepsy is a chronic neurological sleep disorder caused by hypocretin neuron loss, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and intrusions of aspects of rapid eye movement sleep in...
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Updates on structural neuroimaging of narcolepsy with cataplexy

Joo EY

Narcolepsy is a chronic neurological disorder associated with abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and rapid eye movement (REM) sleep phenomena including...
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Parasomnia as an Initial Presentation of Narcolepsy

Kang JJ, Kang HG, Seo MW, Shin BS, Oh SY, Ryu HU

Narcolepsy is characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucinations. Only a few studies have focused on non-rapid eye movement (NREM) and REM parasomnias in narcolepsy. We...
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Spectral Analysis of Polysomnography in Narcolepsy

Yun SH, Choi HD, Seo WS

OBJECTIVE: This study was conducted to identify differences between people with narcolepsy and the normal control of delta and theta activity using electroencephalogram (EEG) spectrum analysis of nocturnal polysomnography (PSG). METHODS:...
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Comparison of Health Related Quality of Life between Type I and Type II Narcolepsy Patients

Cho JW, Kim DJ, Noh KH, Han J, Jung DS

OBJECTIVES: Narcolepsy with cataplexy is a rare chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic/hypnopompic hallucinations. The aims of the present study were comparing the...
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Dysautonomia in Narcolepsy: Evidence by Questionnaire Assessment

Klein G, Burghaus L, Vaillant M, Pieri V, Fink GR, Diederich

BACKGROUND AND PURPOSE: Excessive daytime sleepiness and sudden sleep attacks are the main features of narcolepsy, but rapid-eye-movement sleep behavior disorder (RBD), hyposmia, and depression can also occur. The latter...
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Evaluation of Cognitive Functions in Patients with Narcolepsy

Jin YY, Yoon JS, Chung EK

  • KMID: 2285635
  • J Agric Med Community Health.
  • 2013 Jun;38(2):97-107.
OBJECTIVE: This study aimed to evaluate attention, memory and executive function in patients with narcolepsy. METHODS: This study included 23 narcoleptic patients whose diagnosis were confirmed by the International Classification of...
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Effect of clomipramine in a dog with cataplexy

Jeong SY, Kang MH, Park HM

  • KMID: 1991782
  • Korean J Vet Res.
  • 2013 Jun;53(2):129-131.
A 5-year-old, castrated male, Maltese was presented with history of acute flaccid paralysis. The dog was presented with sudden loss of muscle tone and involuntary movements of hind limbs. Neurologic...
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Sleep disorders medicine

Hong SB

  • KMID: 2342163
  • J Korean Med Assoc.
  • 2013 May;56(5):410-422.
Sleep comprises one third of human life and is very important for maintaining healthy mental and physical states. Sleep disorders disturbing normal sleep are very common and may induce serious...
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Narcolepsy with Obstructive Sleep Apnea in a 4-Year-Old Korean Girl: A Case Report

Kwon S, Jang K, Hwang S, Cho M, Seo H

A 4-yr-old girl has exhibited severe snoring, restless sleep and increasing daytime sleepiness over the last 3 months. The physical examination showed that she was not obese but had kissing...
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Is High IQ Protective Against Cognitive Dysfunction in Narcoleptic Patients?

Yoon SM, Joo EY, Kim JY, Hwang KJ, Hong SB

BACKGROUND AND PURPOSE: The aims of this study were to elucidate the cognitive functions of narcoleptics and determine whether intelligence protects against cognitive dysfunction and depressive mood in these patients. METHODS:...
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Morphological Changes in Narcolepsy

Joo EY

  • KMID: 2202655
  • J Korean Sleep Res Soc.
  • 2013 Dec;10(2):35-38.
Narcolepsy is a chronic neurological disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and manifestations related to rapid eye movement sleep...
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Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment

Cho JW, Jung NY, Bae JW, Kim DJ, Lee JH, Kanbayashi T

  • KMID: 2343436
  • J Korean Neurol Assoc.
  • 2012 Feb;30(1):57-59.
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s....
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Use of PCR with Sequence-specific Primers for High-Resolution Human Leukocyte Antigen Typing of Patients with Narcolepsy

Woo HI, Joo EY, Hong SB, Lee KW, Kang ES

BACKGROUND: Narcolepsy is a neurologic disorder characterized by excessive daytime sleepiness, symptoms of abnormal rapid eye movement (REM) sleep, and a strong association with HLA-DRB1*1501, -DQA1*0102, and -DQB1*0602. Here, we...
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Narcolepsy in Children

Seo WS

  • KMID: 2317500
  • Sleep Med Psychophysiol.
  • 2011 Jun;18(1):17-22.
Childhood narcolepsy is one of the underdiagnosed diseases even the first symptoms often appear in childhood. Making diagnosis through history taking is not always easy because the symptoms of childhood...
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Narcolepsy: Clinical Feature, Diagnosis and Treatment

Shin HB

  • KMID: 2317492
  • Sleep Med Psychophysiol.
  • 2010 Dec;17(2):63-68.
Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with...
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Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients

Joo EY, Tae WS, Kim ST, Hong SB

OBJECTIVE: To investigate gray matter concentration changes in the brains of narcoleptic patients. MATERIALS AND METHODS: Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age,...
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Pediatric Narcolepsy: Diagnosis and Treatment

Bang YW, Chae KY

  • KMID: 2329418
  • J Korean Child Neurol Soc.
  • 2009 Nov;17(2):107-117.
Narcolepsy is chronic devastating disease that characterized by excessive daytime sleepiness, cataplexy, which often precipitated by intense emotion or excitement, hypnagogic, or hypnapompic hallucinations, sleep paralysis and nocturnal disrupted sleep....
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Spectral Analysis of REM Sleep EEG in Narcolepsy and REM Sleep Behavior Disorder

Kim HI, Jeong DU, Park KS

  • KMID: 2317459
  • Sleep Med Psychophysiol.
  • 2008 Jun;15(1):33-38.
INTRODUCTION: It has been proposed that narcolepsy and REM sleep behavior disorder (RBD) have overlapped symptom profile and pathophysiology. This study was aimed at measuring and comparing changes in EEG...
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Linear/Non-Linear Tools and Their Applications to Sleep EEG: Spectral, Detrended Fluctuation, and Synchrony Analyses

Kim JW

  • KMID: 2317455
  • Sleep Med Psychophysiol.
  • 2008 Jun;15(1):5-11.
Sleep is an essential process maintaining the life cycle of the human. In parallel with physiological, cognitive, subjective, and behavioral changes that take place during the sleep, there are remarkable...
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