J Korean Ophthalmol Soc.  2017 Feb;58(2):165-170. 10.3341/jkos.2017.58.2.165.

Comparison of Inner Retinal Thickness between the Fellow Eyes of Unilateral Branch Retinal Vein Occlusion and Normal Control

• Chung GC
• Lee DE
• Yoon CK
• Kim HW
• Kim JL

• KMID: 2369463
• DOI: http://doi.org/10.3341/jkos.2017.58.2.165

Abstract

PURPOSE
The purpose of this study was to compare inner retinal thickness and retinal nerve fiber layer (RNFL) thickness between fellow eyes with unilateral branch retinal vein occlusion (BRVO) and normal control eyes.
METHODS
Retrospective cross-sectional study including 59 patients diagnosed with unilateral BRVO and 51 control subjects. Using spectral domain optical coherence tomography, we investigated the average, 4 quadrant, and 12 clock-hour RNFL thicknesses and the average, minimum, superior, superonasal, superotemporal, inferior, inferonasal, and inferotemporal thicknesses of the ganglion cell-inner plexiform layer (GCIPL) layer.
RESULTS
Patients with unilateral BRVO had a higher incidence of hypertension. In the fellow eyes of the unilateral BRVO patients, 7 and 11 o'clock RNFL thicknesses were significantly thinner than for the control eyes. There was no significant difference in the GCIPL thickness between the two groups
CONCLUSIONS
The RNFL thickness of the fellow eyes of the unilateral BRVO patients showed significant decreases in the 7 and 11 o'clock sectors (p=0.005, 0.017, respectively), whereas there was no significant difference in the GCIPL thickness between the two groups. In the RNFL thickness analysis, the 7 and 11 o'clock sectors were found to be dominant locations of decreased RNFL thickness for the open angle glaucoma. Further, glaucomatous change should be carefully monitored in the fellow eyes of unilateral BRVO patients.

Keyword

Fellow eye; Ganglion cell layer thickness; Glaucoma; Retinal nerve fiber layer thickness; Unilateral retinal vein occlusion

MeSH Terms

Cross-Sectional Studies
Ganglion Cysts
Glaucoma
Glaucoma, Open-Angle
Humans
Hypertension
Incidence
Nerve Fibers
Retinal Vein Occlusion*
Retinal Vein*
Retinaldehyde*
Retrospective Studies
Tomography, Optical Coherence
Retinaldehyde

Figure

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  Figure 1. Photographs of the retinal nerve fiber layer (RNFL) of a 65 year old man with branch retinal vein occlusion (BRVO) (A, B). This patient had BRVO in the left eye (B) and red-free fundus photography showed a wedge-shaped defect (between arrows) in the right eye (A). Optical coherence tomography (C) of the right eye showed that RNFL thickness was identified as abnormal by the <1% criterion from 10-o’clock to 11-o’clock area. Ganglion cell analysis map of the right eye showed thinning of the ganglion cell-inner plexiform layer (red color area) on deviation map of right eye. A glaucomatous visual field change was noted in the corre-sponding hemifield location (D). TEMP = temporal; SUP = superior; NAS = nasal; INF = inferior; S = superior; N = nasal; I = inferior; T = temporal; MD = mean deviation; PSD = pattern standard deviation.

Reference

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