J Korean Ophthalmol Soc.  2009 Jan;50(1):120-127. 10.3341/jkos.2009.50.1.120.

Evaluation of Glaucomatous Damage in the Fellow Eyes of Patients With Unilateral Retinal Vein Occlusion

• Yoon SY
• Choi J
• Lee CH
• Seong M
• Sung KR
• Kook MS

• KMID: 2211906
• DOI: http://doi.org/10.3341/jkos.2009.50.1.120

Abstract

PURPOSE
To investigate the visual field (VF) and retinal nerve fiber layer (RNFL) status of the fellow eyes in patients with unilateral retinal vein occlusion (RVO).
METHODS
Fifty patients with unilateral RVO and 35 normal control subjects wereconsecutively recruited. Humphrey VF parameters and RNFL status using scanning laser polarimetry with variable corneal compensation (GDx-VCC) were compared between the fellow eyes of the patients with unilateral RVO and control eyes. We also assessed the risk factors for the development of glaucomatous damage in the fellow eyes of unilateral RVO patients.
RESULTS
Twelve fellow eyes out of 50 patients with unilateral RVO showed glaucomatous VF and RNFL changes assessed by GDx-VCC. VF indices and RNFL thickness parameters in the study group were significantly lower than those in the control group (p<0.05). Increased age and vertical cup-to-disc ratio were significantly associated with severity of VF and RNFL damage in the fellow eye of unilateral RVO patients (p<0.05).
CONCLUSIONS
The fellow eyes in patients with unilateral RVO showed significantly worse VF indices and lower RNFL thickness than normal control eyes. The glaucomatous change should be carefully monitored in the fellow eyes of unilateral RVO patients.

Keyword

BRVO; CRVO; Fellow eye; Glaucoma; Retinal vein occlusion

MeSH Terms

Compensation and Redress
Eye
Glaucoma
Humans
Nerve Fibers
Retinal Vein
Retinal Vein Occlusion
Retinaldehyde
Risk Factors
Scanning Laser Polarimetry
Visual Fields
Retinaldehyde

Figure

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  Figure 1. Comparison of visual field indices of the fellow eyes of branch retinal vein occlusion (BRVO) patients, the fellow eyes of central retinal vein occlusion (CRVO) patients and controls; MD=mean deviation; PSD=pattern standard deviation; BRVO=branch retinal vein occlusion; CRVO=central retinal vein * Statistical significance was found with occlusion; unpaired t-test (p<0.001).

• 

  Figure 2. Global and sectoral RNFL retardation values based on GDx-VCC of the fellow eyes of branch retinal vein occlusion (BRVO) patients, the fellow eyes of central retinal vein occlusion (CRVO) patients and controls; TSNIT=temporal, superior, nasal, inferior and temporal AV=average; SD=standard deviation; BRVO= branch retinal vein occlusion; CRVO=central retinal vein occlusion; * Statistical significance was found with unpaired t-test (p<0.001).

Reference

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