Osteoporos Sarcopenia.  2016 Dec;2(4):221-227. 10.1016/j.afos.2016.10.004.

Relationship between the FRAX® score and falls in community-dwelling middle-aged and elderly people

  • 1Department of Family Medicine, Antai Medical Cooperation Tien Sheng Memorial Hospital, PingTung, Taiwan.
  • 2Department of Nursing, Meiho University, PingTung, Taiwan.
  • 3College of Education, National Kaohsiung Normal University, Kaohsiung, Taiwan.
  • 4Department of Family Medicine, National Cheng Kung University Hospital, Tainan, Taiwan. paulo@mail.ncku.edu.tw
  • 5Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
  • 6Department of Orthopedics, Tainan Municipal An-Nan Hospital-China Medical University, Tainan, Taiwan.
  • 7Institute of Gerontology, National Cheng Kung University Medical College, Tainan, Taiwan.


Falls is a risk factor for fracture. The FRAX® predicts fractures. Whether the FRAX® is associated with fall in both gender is inconclusive. The aim of our study is to evaluate the association between FRAX scores and falls.
The cross-sectional study set from 2009 to 2010 included 1200 community-dwelling people who were systematically sampled in central Taiwan. The 1200 participants (men: 524; women: 676; ≥40 years old) completed questionnaires about socioeconomic status; lifestyle; medical and fall history were completed. FRAX scores with and without bone mineral density (BMD) were calculated by using the Taiwan calculator.
A total of 19.8% participants fell down. Binary regression models showed that diabetes mellitus history (OR: 1.61; 95% CI: 1.03-2.52), the FRAX without BMD in a continuous major score (OR: 1.06; 95% CI: 1.03-1.09), continuous hip score (OR: 1.11; 95% CI: 1.05-1.16), categorical major score ≥ 10% (OR: 1.81; 95% CI: 1.25-2.61), and categorical hip score ≥ 3% (OR: 1.80; 95% CI: 1.30-2.50) were independent risk factors for falls. FRAX with BMD in a continuous major score (OR: 1.04; 95% CI: 1.02-1.06), continuous hip score (OR: 1.06; 95% CI: 1.02-1.09), categorical major score ≥ 10% (OR: 1.52; 95% CI: 1.09-2.12), and categorical hip score ≥ 3% (OR: 1.53; 95% CI: 1.13-2.09) were also independent risk factors.
We concluded that FRAX® scores with and without BMD were unanimously correlated with falls in community-dwelling middle-aged and elderly males and females.


FRAX; Falls; Diabetes mellitus (DM); Community; Fracture
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