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The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin

Lin YP, Chang YF

Adhesion through microbial surface components that recognize adhesive matrix molecules is an essential step in infection for most pathogenic bacteria. In this study, we report that LigB interacts with fibronectin...
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In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin

Kim D, Kordick D, Divers T, Chang YF

Antimicrobial susceptibility testing was conducted with 6 different spirochetal strains (4 strains of Leptospira spp. and 2 strains of Borrelia burgdorferi) against 3 antimicrobial agents, commonly used in equine and...
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Equine hyperimmune serum protects mice against Clostridium difficile spore challenge

Yan W, Shin KS, Wang SJ, Xiang H, Divers T, McDonough , Bowman J, Rowlands A, Akey B, Mohamed H, Chang YF

Clostridium (C.) difficile is a common cause of nosocomial diarrhea in horses. Vancomycin and metronidazole have been used as standard treatments but are only moderately effective, which highlights the need...
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Relationship between the FRAX® score and falls in community-dwelling middle-aged and elderly people

Ou LC, Chang YF, Chang CS, Chao TH, Lin RM, Sun ZJ, Wu CH

OBJECTIVES: Falls is a risk factor for fracture. The FRAX® predicts fractures. Whether the FRAX® is associated with fall in both gender is inconclusive. The aim of our study is...
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A biosensor assay for the detection of Mycobacterium avium subsp. paratuberculosis in fecal samples

Kumanan V, Nugen SR, Baeumner A, Chang YF

A simple, membrane-strip-based lateral-flow (LF) biosensor assay and a high-throughput microtiter plate assay have been combined with a reverse transcriptase polymerase chain reaction (RT-PCR) for the detection of a small...
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Comparative antibody response of five recombinant antigens in related to bacterial shedding levels and development of serological diagnosis based on 35 kDa antigen for Mycobacterium avium subsp. paratuberculosis

Shin SJ, Yoo HS, McDonough , Chang YF

  • KMID: 1120066
  • J Vet Sci.
  • 2004 Jun;5(2):111-117.
Eighty-five complex (85A, 85B and 85C), 35-kDa and superoxide dismutase (SOD) were cloned, expressed and purified as antigens in an enzyme-linked immunosorbent assay (ELISA) to compare the serological reactivity of...
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