Ann Dermatol.  2016 Dec;28(6):789-791. 10.5021/ad.2016.28.6.789.

A Case of Cutaneous Epstein-Barr Virus-Associated Diffuse Large B-Cell Lymphoma in an Angioimmunoblastic T-Cell Lymphoma

• Lee MH
• Moon IJ
• Lee WJ
• Won CH
• Chang SE
• Choi JH
• Lee MW

• KMID: 2368141
• DOI: http://doi.org/10.5021/ad.2016.28.6.789

Abstract

No abstract available.

MeSH Terms

B-Lymphocytes*
Lymphoma, B-Cell*
Lymphoma, T-Cell*
T-Lymphocytes*

Figure

• 

  Fig. 1 (A) Clinical photographs of initial angioimmunoblastic T-cell lymphoma and (B) secondary cutaneous diffuse large B-cell lymphoma.

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  Fig. 2 Histopathological findings for initial angioimmunoblastic T-cell lymphoma (AITL) of lymph node (A~C) and secondary diffuse large B-cell lymphoma (DLBCL) of skin (D~F). (A) Polymorphic cellular infiltration in lymph node (H&E, ×400). (B) Epstein-Barr virus (EBV)-positive cells were not detected by in situ hybridization for EBV RNA (×200). (C) Immunophenotype by staining for BCL-6, a marker of follicular helper T cells in AITL (immunoperoxidase stain for BCL-6, ×400). (D) medium to large-sized cellular infiltration in dermis (H&E, ×400). (E) EBV-positive cells were detected by in situ hybridization for EBV RNA (×200). (F) Immunophenotype by staining for CD20, a marker of B cells in DLBCL (immunoperoxidase stain for CD20, ×100).

Reference

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