Ann Dermatol.  2023 Nov;35(Suppl2):S317-S322. 10.5021/ad.22.105.

Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma with Epidermotropism

• Lee GH
• Pyo GJ
• Myung KB
• Kwon ES

• KMID: 2548882
• DOI: http://doi.org/10.5021/ad.22.105

Abstract

Primary cutaneous B-cell lymphomas are rare diseases comprising nodular to diffuse lymphoid cell infiltration with an overlying grenz zone and no epidermal involvement upon histological analysis. Diagnostics can become challenging when lymphomas exhibit the characteristics of both B and T-cells. Differential diagnoses may include reactive proliferations, cutaneous composite lymphomas, and transformed mycosis fungoides. Immunohistochemistry and gene arrangement tests may be beneficial to clarify the diagnosis. Herein, we report a rare case of epidermotropic EBV-positive cutaneous B-cell lymphoma along with a literature review.

Keyword

Cutaneous B-cell lymphoma; Epidermotropism; Epstein-Barr virus