Korean J Pathol.  1996 Aug;30(8):739-741.

Adenoid Basal Carcinoma Associated with Invasive Squamous Cell Carcinoma of Uterine Cervix: A case report

• Kim HJ
• Kim DW
• Jin SY
• Lee DW

Abstract

Adenoid basal carcinoma of the uterine cervix is a rare neoplasm that accounts for less than 1% of cervical adenocarcinomas. Though it has been confused with adenoid cystic carcinoma, it is now distinctly recognized by better prognosis and different histologic and immunohistochemical findings. We have experienced a case of adenoid basal carcinoma associated with invasive squamous cell carcinoma of the uterine cervix in a 52-year-old woman. The tumor was composed of small, round to oval nests of basaloid cells with peripheral palisading. Some of the nests showed central cystic spaces, or cribriform pattern, and central squamous differentiation with cytological atypia. Invasive squamous cell carcinoma was located adjacent to the adenoid basal carcinoma without any transition between these two lesions. Immunohistochemically, the tumor cells disclosed positive staining for cytokeratin, but negative reaction for CEA, EMA, and S-100 protein.

Keyword

Adenoid basal carcinoma; Invasive squamous cell carcinoma; Uterine cervix; Immunohistochemical staining

MeSH Terms

Adenocarcinoma
Adenoids*
Carcinoma, Adenoid Cystic
Carcinoma, Squamous Cell*
Cervix Uteri*
Female
Humans
Keratins
Middle Aged
Prognosis
S100 Proteins
Keratins
S100 Proteins