Yonsei Med J.  2015 Jul;56(4):1021-1027. 10.3349/ymj.2015.56.4.1021.

Effect of a Low Iodine Diet vs. Restricted Iodine Diet on Postsurgical Preparation for Radioiodine Ablation Therapy in Thyroid Carcinoma Patients

Affiliations
  • 1Department of Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • 2Department of Food and Nutrition, College of Human Ecology, Yonsei University, Seoul, Korea.
  • 3Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 4Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 5Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. woungyounc@yuhs.ac

Abstract

PURPOSE
The radioiodine ablation therapy is required for patients who underwent a total thyroidectomy. Through a comparative review of a low iodine diet (LID) and a restricted iodine diet (RID), the study aims to suggest guidelines that are suitable for the conditions of Korea.
MATERIALS AND METHODS
The study was conducted with 101 patients. With 24-hour urine samples from the patients after a 2-week restricted diet and after a 4-week restricted diet, the amount of iodine in the urine was estimated. The consumed radioiodine amounts for 2 hours and 24 hours were calculated.
RESULTS
This study was conducted with 47 LID patients and 54 RID patients. The amounts of iodine in urine, the 2-week case and 4-week case for each group showed no significant differences. The amounts of iodine in urine between the two groups were both included in the range of the criteria for radioiodine ablation therapy. Also, 2 hours and 24 hours radioiodine consumption measured after 4-week restrictive diet did not show statistical differences between two groups.
CONCLUSION
A 2-week RID can be considered as a type of radioiodine ablation therapy after patients undergo a total thyroidectomy.

Keyword

Thyroid carcinoma; iodine diet; radioiodine ablation therapy

MeSH Terms

Ablation Techniques
Adult
Carcinoma/metabolism/*radiotherapy/surgery
*Diet
Female
Humans
Iodides/urine
Iodine/administration & dosage/urine
Iodine Radioisotopes/metabolism/*therapeutic use
Male
Middle Aged
Republic of Korea
Thyroid Neoplasms/metabolism/*radiotherapy/surgery
Thyroidectomy
Treatment Outcome
Iodides
Iodine
Iodine Radioisotopes

Cited by  1 articles

The Impact of Low Adherence to the Low-iodine Diet on the Efficacy of the Radioactive Iodine Ablation Therapy
Dal Lae Ju, Young Joo Park, Hee-Young Paik, YoonJu Song
Clin Nutr Res. 2015;4(4):267-271.    doi: 10.7762/cnr.2015.4.4.267.


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