Ann Lab Med.  2015 Mar;35(2):257-259. 10.3343/alm.2015.35.2.257.

BRAF V600E and MAP2K1 Mutations in Hairy Cell Leukemia and Splenic Marginal Zone Lymphoma Cases

Affiliations
  • 1Department of Laboratory Medicine & Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sunnyhk@skku.edu, nb.seungtae.lee@gmail.com
  • 2Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Adult
Aged
Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Cyclophosphamide/therapeutic use
Doxorubicin/therapeutic use
Female
Humans
Immunoglobulin Variable Region/genetics
Leukemia, Hairy Cell/drug therapy/*genetics/pathology
Lymphoma, Non-Hodgkin/drug therapy/*genetics/pathology
MAP Kinase Kinase 1/*genetics
Male
Middle Aged
Mutation
Polymorphism, Single Nucleotide
Prednisone/therapeutic use
Pregnancy
Proto-Oncogene Proteins B-raf/*genetics
Real-Time Polymerase Chain Reaction
Vincristine/therapeutic use
Cyclophosphamide
Doxorubicin
Immunoglobulin Variable Region
MAP Kinase Kinase 1
Prednisone
Proto-Oncogene Proteins B-raf
Vincristine

Cited by  1 articles

Efficacy of Annexin A1 Immunostaining in Bone Marrow for the Diagnosis of Hairy Cell Leukemia
Chang-Hun Park, Hyun-Young Kim, Sang-Yong Shin, Hee-Jin Kim, Chul Won Jung, Jong-Won Kim, Sun-Hee Kim
Lab Med Online. 2019;9(4):236-241.    doi: 10.3343/lmo.2019.9.4.236.


Reference

1. Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, et al. BRAF mutations in hairy-cell leukemia. N Engl J Med. 2011; 364:2305–2315. PMID: 21663470.
2. Xi L, Arons E, Navarro W, Calvo KR, Stetler-Stevenson M, Raffeld M, et al. Both variant and IGHV4-34-expressing hairy cell leukemia lack the BRAF V600E mutation. Blood. 2012; 119:3330–3332. PMID: 22210875.
Article
3. Waterfall JJ, Arons E, Walker RL, Pineda M, Roth L, Killian JK, et al. High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias. Nat Genet. 2014; 46:8–10. PMID: 24241536.
Article
4. Foucar K, Falini B, Catovsky D, Stein H. Hairy cell leukaemia. In : Swerdlow S, Campo E, Harris NL, editors. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon, France: International Agency for Research on Cancer;2008. p. 188–190.
5. Park SJ, Sun JY, Hong K, Kwak JY, Kim EK, Chung WY, et al. Application of BRAF, NRAS, KRAS mutations as markers for the detection of papillary thyroid cancer from FNAB specimens by pyrosequencing analysis. Clin Chem Lab Med. 2013; 51:1673–1680. PMID: 23585181.
Article
6. Lee ST, Kim JY, Kown MJ, Kim SW, Chung JH, Ahn MJ, et al. Mutant enrichment with 3'-modified oligonucleotides a practical PCR method for detecting trace mutant DNAs. J Mol Diagn. 2011; 13:657–668. PMID: 21979247.
7. Davidsson J, Lilljebjorn H, Panagopoulos I, Fioretos T, Johansson B. BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias. Leukemia. 2008; 22:1619–1621. PMID: 18273045.
Article
8. Trifa AP, Popp RA, Cucuianu A, Coada CA, Urian LG, Militaru MS, et al. Absence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms. Leuk Lymphoma. 2012; 53:2496–2497. PMID: 22339435.
Article
9. Verma S, Greaves WO, Ravandi F, Reddy N, Bueso-Ramos CE, O'Brien S, et al. Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay. Am J Clin Pathol. 2012; 138:153–156. PMID: 22706871.
10. Laurini JA, Aoun P, Iqbal J, Chan W, Greiner TC. Investigation of the BRAF V600E mutation by pyrosequencing in lymphoproliferative disorders. Am J Clin Pathol. 2012; 138:877–883. PMID: 23161722.
Full Text Links
  • ALM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr