Ann Dermatol.  2002 Mar;14(1):38-41. 10.5021/ad.2002.14.1.38.

A Case of Bowen's Disease Partially Responded to Photodynamic Therapy

• Lee SH
• Jung BC
• Woo MJ
• Kim DS
• Kim SW

• KMID: 2362385
• DOI: http://doi.org/10.5021/ad.2002.14.1.38

Abstract

Photodynamic therapy(PDT) is a treatment modality by highly reactive oxygen intermediates generated through the interaction of light with a photosensiziter. It has been shown to be an effective treatment for various cutaneous and noncutaneous malignancies. It is efficient for the curative and palliative treatment of epithelial skin tumor in situ or early invasive lesions. In effect, it is a useful alternative treatment for the lesions located on anatomically difficult areas or the large-sized lesions. We treated a case of Bowen's disease arising on the plantar area and 3rd and 4th toewebs of left forefoot in a 61-year-old man with PDT using the hematoporphyrin derivative, porfirmer sodium(Photofrin, Russia) as a photosensitizer and gold vapor laser as a visible light source. The outcome showed partial clinical improvement after about 2 months' follow-up.

Keyword

Photodynamic therapy; Porfirmer sodium; Bowen's disease

MeSH Terms

Bowen's Disease*
Follow-Up Studies
Hematoporphyrin Derivative
Humans
Lasers, Gas
Light
Middle Aged
Oxygen
Palliative Care
Photochemotherapy*
Skin
Hematoporphyrin Derivative
Oxygen