Korean J Dermatol.  2007 Mar;45(3):237-241.

Photodynamic Therapy for Treatment of Bowen's Disease

• Kim YJ
• Kang HY
• Lee ES
• Kim YC

Abstract

BACKGROUND: Photodynamic therapy (PDT) is increasingly used for superficial skin cancers. However, there have only been a few reports on Bowen's disease treated with PDT in the Korean literature.
OBJECTIVE
The purpose of this study was to evaluate the effectiveness and side effects of PDT in the treatment of Bowen's disease.
METHODS
We treated 20 Bowen's disease lesions in 15 patients using topical PDT containing 5-aminolaevulinic acid and a light-emitting diode device. The light intensity used was 100 mW/cm(2) and the dosage was 140~220 J/cm(2).
RESULTS
Complete clearance was achieved in 17 of 20 lesions (85%) after 2~4 treatment sessions. The only side effect was a stinging sensation, which occurred in 5 lesions (20%).
CONCLUSION
PDT is a relatively effective and useful alternative therapy for treatment of Bowen's disease.

Keyword

Bowen's disease; Photodynamic therapy

MeSH Terms

Bites and Stings
Bowen's Disease*
Humans
Photochemotherapy*
Sensation
Skin Neoplasms