Ann Dermatol.  1993 Jan;5(1):1-4. 10.5021/ad.1993.5.1.1.

Detection of Human Papillomavirus DNA in Genital and Laryngeal Papilloma Using the Polymerase Chain Reaction

• Park HJ
• Park KC

• KMID: 2361724
• DOI: http://doi.org/10.5021/ad.1993.5.1.1

Abstract

BACKGROUND
Compared to condyloma acuminatum, the cause of laryngeal papilloma has not been clearly established. Although mode of viral transmission is not known yet, laryngeal papilloma seems to be caused by same viruses as condyloma acuminatum.
OBJECTIVE
This study was done to investigate the HPV types of condyloma acuminatum and laryngeal papilloma and the epidemiologic relationship between these two diseases.
METHODS
The polymerase chain reaction (PCR) was done in fifteen cases of condyloma acuminatum and ten cases of laryngeal papilloma.
RESULTS
Same types of HPV DNA (HPV6,11) were detected in all cases of condyloma acuminatum and laryngeal papilloma.
CONCLUSION
Laryngeal papilloma is considered a pure viral disease caused by HPV 6 or HPVll and closely related to condyloma acuminatum caused by HPV 6, 11.

Keyword

Condyloma acuminatum; Laryngeal papilloma; Human papillomavirus

MeSH Terms

DNA*
Human papillomavirus 6
Humans*
Papilloma*
Polymerase Chain Reaction*
Virus Diseases
DNA