Ann Dermatol.  1996 Jan;8(1):25-29. 10.5021/ad.1996.8.1.25.

A Case of Langerhans Cell Histiocytosis in an Adult

• Jung WK
• Kim YK
• Whang KW
• Lee HK
• Park HS
• Won JH

• KMID: 2361341
• DOI: http://doi.org/10.5021/ad.1996.8.1.25

Abstract

Langerhans sell bistiocytosis(LCH) is a reactive disease in which abnomal Langerhans cells accurnulate in various body sites and cause damage to affected organs. LCH usually occurs in childrea bur can also affect adults although rarely. LCH in a case of 65-year-old man initially involwed the lymph nodes (left supraclacicular and right inguinal area) and pelvis bone, and eight months later curancous involvement was noted. The skin lesions were waxy from the waxy papules showed that the dense infiltrate, ptedominantly of histiocytes, was present in the dermis, Immunohistochemistry for S-100 protein showed positive staining snd electron miscoroscopy disclosed Birbeck granules, which is characteristic findings of Langerhans cells.

Keyword

Langerhans cell histiocytosis; Old age; Lymph nodes

MeSH Terms

Adult*
Aged
Dermis
Histiocytes
Histiocytosis, Langerhans-Cell*
Humans
Immunohistochemistry
Langerhans Cells
Lymph Nodes
Pelvis
S100 Proteins
Skin
S100 Proteins