J Korean Ophthalmol Soc.  1996 Nov;37(11):1946-1950.

A Case of Orbital Langerhans' cell histiocytosis

• Shin JC

Abstract

Langerhans' cell histiocytosis is a rare childhood disease of unknown etiology that is characterized by abnormal proliferation and infiltration of histiocytic cells in various tissues. The authors experienced a case of Langerhans' cell histiocytosis in 4-year-old man who had swelling of the right upper eyelid. Radiologic examination demonstrates a osteolytic soft tissue mass in the right orbit. The light microscopic and electromicroscopic examinations demonstrates a number of histiocytes containing its cytoplasmic racket-shaped Birbeck granule. Then, we confirmed the Langerhans' cell histiocytosis in the right orbit and the radiotherapy was performed. No recurrence occured more than four years after the initial radiotherapy.

Keyword

Birbeck granule; Langerhans' cell histiocytosis

MeSH Terms

Child, Preschool
Cytoplasm
Eyelids
Histiocytes
Histiocytosis*
Humans
Orbit*
Radiotherapy
Recurrence