Allergy Asthma Respir Dis.  2016 Nov;4(6):449-452. 10.4168/aard.2016.4.6.449.

Anaphylaxis after consumption of abalone

• Yu J
• Son ES
• Kim J
• Park HS
• Lee S
• Lee SM
• Park JW
• Lee SP

• KMID: 2361261
• DOI: http://doi.org/10.4168/aard.2016.4.6.449

Abstract

Abalone is popular seafood in Asia; however, allergy to abalone was rarely reported. We report a case of anaphylaxis after consumption of abalone. A 24-year-old female visited an Emergency Department, complaining of cough, dyspnea, rhinorrhea, generalized urticaria, facial edema, and wheezing that had developed 1 hour after consumption of abalone. She was discharged when her symptoms subsided after antihistamine and dexamethasone were given. One month later, she was referred to our outpatient clinic. We performed skin prick tests, measurement of serum specific IgE antibody level, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with IgE immunoblotting. Both skin prick and specific IgE antibody tests were positive for abalone crude extract. In SDS-PAGE with IgE immunoblotting, we identified possible antigens sized 55, 100, and 25 kDa, respectively. This is the first case of abalone-induced anaphylaxis in Korea.

Keyword

Anaphylaxis; Food allergy; Abalone; Shellfish

MeSH Terms

Ambulatory Care Facilities
Anaphylaxis*
Asia
Cough
Dexamethasone
Dyspnea
Edema
Electrophoresis
Electrophoresis, Polyacrylamide Gel
Emergency Service, Hospital
Female
Food Hypersensitivity
Humans
Hypersensitivity
Immunoblotting
Immunoglobulin E
Korea
Respiratory Sounds
Seafood
Shellfish
Skin
Sodium
Urticaria
Young Adult
Dexamethasone
Immunoglobulin E
Sodium

Figure

• 

  Fig. 1 IgE reactivity of sera to abalone measured by enzyme-linked immunosorbent assay. Bla, blank control.

• 

  Fig. 2 Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the abalone protein. Lane M, molecular mass marker; Lane rAE, raw abalone's epipodium; Lane rAI, raw abalone's intestines; Lane sAE, steamed abalone's epipodium; Lane sAI, steamed abalone's intestines (steamed).

• 

  Fig. 3 IgE immunoblotting of the abalone protein with sera of patients and healthy control. ABE, abalone's epipodium; ABI, abalone's intestines.

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