Tissue Eng Regen Med.  2016 Apr;13(2):191-199. 10.1007/s13770-016-9126-x.

Osseointegration of Magnesium-Incorporated Sand-Blasted Acid-Etched Implant in the Dog Mandible: Resonance Frequency Measurements and Histomorphometric Analysis

• Song WW
• Heo JH
• Lee JH
• Park YM
• Kim YD

• KMID: 2360859
• DOI: http://doi.org/10.1007/s13770-016-9126-x

Abstract

The aim of this pilot study was to investigate the bone responses of novel magnesium (Mg)-incorporated sand-blasted and acid-etched (SLA) titanium (Ti) implant in an experimental animal model. Novel Mg-incorporated SLA Ti implant was obtained via vacuum arc source ion implantation method and Mg-ions were implanted into the SLA implant surface. Control group consisted of two commercial implants; resorbable blasting media (RBM) and SLA. Twelve implants from each group were placed into the mandibles of 6 mongrel dogs. Experimental animals were divided into 2 groups of 3 animals, with 4 weeks and 8 weeks healing time points. Resonance frequency analysis was performed at the time of fixture installation, 1, 2, 4, and 8 weeks after installation. Bone to implant contact (BIC) measurements were assessed at the 4 and 8 weeks healing time points. The overall implant survival rate was 97.2%. The Mg-incorporated SLA Ti implants showed more rapid osseointegration than control group implants at follow-up periods of 4 weeks. Histomorphometric analysis showed a tendency for BIC% values of Mg-incorporated SLA Ti implant to be higher than that of other the implant groups. The results of this study suggest that Mg-incorporated SLA Ti implant may be effective in enhancing the bone responses by rapid osseointegration in early healing periods.

Keyword

Dental implant; Animal study; Surface treatment; Bone to implant contact; Bone metabolism

MeSH Terms

Animals
Dental Implants
Dogs*
Follow-Up Studies
Magnesium
Mandible*
Methods
Models, Animal
Osseointegration*
Pilot Projects
Survival Rate
Titanium
Vacuum
Dental Implants
Magnesium
Titanium