Korean J Urol.  2015 Dec;56(12):803-810. 10.4111/kju.2015.56.12.803.

Urodynamic assessment of bladder and urethral function among men with lower urinary tract symptoms after radical prostatectomy: A comparison between men with and without urinary incontinence

• Lee H
• Kim KB
• Lee S
• Lee SW
• Kim M
• Cho SY
• Oh SJ
• Jeong SJ

• KMID: 2359872
• DOI: http://doi.org/10.4111/kju.2015.56.12.803

Abstract

PURPOSE
We compared bladder and urethral functions following radical prostatectomy (RP) between men with and without urinary incontinence (UI), using a large-scale database from SNU-experts-of-urodynamics-leading (SEOUL) Study Group.
MATERIALS AND METHODS
Since July 2004, we have prospectively collected data on urodynamics from 303 patients with lower urinary tract symptoms (LUTS) following RP at three affiliated hospitals of SEOUL Study Group. After excluding 35 patients with neurogenic abnormality, pelvic irradiation after surgery, or a history of surgery on the lower urinary tract, 268 men were evaluated. We compared the urodynamic findings between men who had LUTS with UI (postprostatectomy incontinence [PPI] group) and those who had LUTS without UI (non-PPI group).
RESULTS
The mean age at an urodynamic study was 68.2 years. Overall, a reduced bladder compliance (< or =20 mL/cmH2O) was shown in 27.2% of patients; and 31.3% patients had idiopathic detrusor overactivity. The patients in the PPI group were older (p=0.001) at an urodynamic study and had a lower maximum urethral closure pressure (MUCP) (p<0.001), as compared with those in the non-PPI group. Bladder capacity and detrusor pressure during voiding were also significantly lower in the PPI group. In the logistic regression, only MUCP and maximum cystometric capacity were identified as the related factor with the presence of PPI.
CONCLUSIONS
In our study, significant number of patients with LUTS following RP showed a reduced bladder compliance and detrusor overactivity. PPI is associated with both impairment of the urethral closuring mechanism and bladder storage dysfunction.

Keyword

Prostate; Prostatectomy; Urodynamics

MeSH Terms

Aged
Humans
Male
Middle Aged
Prospective Studies
Prostatectomy/*adverse effects/methods
Urethra/*physiopathology
Urinary Bladder/*physiopathology
Urinary Bladder, Overactive/complications
Urinary Incontinence/*etiology/physiopathology
Urodynamics/physiology

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