Ewha Med J.  2016 Oct;39(4):122-124. 10.12771/emj.2016.39.4.122.

Anti-tuberculosis Treatment-Induced Insulin Autoimmune Syndrome

• Han JS
• Moon HJ
• Kim JS
• Kim HI
• Kim CH
• Kim MJ

• KMID: 2356384
• DOI: http://doi.org/10.12771/emj.2016.39.4.122

Abstract

Insulin autoimmune syndrome, a rare cause of endogenous hyperinsulinemic hypoglycemia, is characterized by insulin autoantibody, hyperinsulinemia and fasting hypoglycemia. It is well known that drugs containing a sulfhydryl group such as methimazole or α-mercaptopropionyl glycine can induce insulin autoimmune syndrome. However, insulin autoimmune syndrome caused by anti-tuberculosis treatment is very rare. We report a case of insulin autoimmune syndrome after anti-tuberculosis treatment with a review of the relevant literature.

Keyword

Hypoglycemia; Insulin autoimmune syndrome; Tuberculosis

MeSH Terms

Glycine
Hyperinsulinism
Hypoglycemia
Insulin*
Methimazole
Tuberculosis
Glycine
Insulin
Methimazole

Figure

• 

  Fig. 1 Images of pancreas. Abdominal computed tomography (A) and endoscopic ultrasonography (B) show no evidence of intra-abdominal mass.

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