J Cerebrovasc Endovasc Neurosurg.  2016 Sep;18(3):194-200. 10.7461/jcen.2016.18.3.194.

Efficacy of Pre-procedural Rehydration against Thromboembolic Complications for Ruptured Aneurysm Embolization

• Park SD
• Jung YJ

• KMID: 2355641
• DOI: http://doi.org/10.7461/jcen.2016.18.3.194

Abstract

OBJECTIVE
To report effects of the pre-procedural rehydration for reduce thromboembolic complications in acute phase aneurysmal subarachnoid hemorrhage coil embolization.
MATERIALS AND METHODS
From January 2009 to December 2013, 190 patients with ruptured aneurysmal subarachnoid hemorrhage (aSAH) treated by coil embolization at our institution were consecutively enrolled in this study. In period 1 (from January 2009 to June 2012, n = 122), pre-procedural fluid was not supplied. In period 2 (from July 2012 to December 2013, n = 68), depending on the state of the patient's body weight and degree of dehydration, intravenous fluid was started with infusion of approximately 7 mL/kg of 0.9 percent saline (minimum 300 to maximum 500 mL) over 30 minutes.
RESULTS
A total of 190 patients were hospitalized due to aSAH and underwent coil embolization for five years between January 2009 and December 2013. Of these, 122 patients underwent coil embolization based on the old protocol before June 2012 (period 1) and 68 underwent the procedure based on the new protocol after the period 2. Neck size, width, maximum diameter of the aneurysm and procedure time were associated with procedure related thromboembolic complications in entire periods (multivariate analysis, p < 0.05, in respectively). The frequency of thromboembolism showed a drastic decrease in period 2 (re-hydration period), from 18.0% (22/123) to 4.4% (3/67), which was also statistically significant (p = 0.007, Chi-square test).
CONCLUSION
Pre-procedural administration of a sufficient dose of fluid considering the patient's dehydration reduced the frequency of thromboembolism in cases of emergency coil embolization for ruptured aneurysm, without increasing additional specific complications.

Keyword

Subarachnoid hemorrhage; Embolization; Complications; Rehydration solutions

MeSH Terms

Aneurysm
Aneurysm, Ruptured*
Body Weight
Dehydration
Embolization, Therapeutic
Emergencies
Fluid Therapy*
Humans
Neck
Rehydration Solutions
Subarachnoid Hemorrhage
Thromboembolism
Rehydration Solutions

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