Intest Res.  2016 Oct;14(4):297-304. 10.5217/ir.2016.14.4.297.

Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place

• Abdul Rani R
• Raja Ali R
• Lee YY

• KMID: 2354947
• DOI: http://doi.org/10.5217/ir.2016.14.4.297

Abstract

Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm.

Keyword

Irritable bowel syndrome; Inflammatory bowel disease; Gut-brain axis; IBS-IBD overlap syndrome

MeSH Terms

Accidental Falls*
Asia
Incidence
Inflammatory Bowel Diseases*
Irritable Bowel Syndrome*
Prevalence