J Korean Acad Oral Health.  2016 Sep;40(3):183-189. 10.11149/jkaoh.2016.40.3.183.

Caries prediction using the caries activity test with a sulfisomidine mixture: a 3-year follow-up study

Affiliations
  • 1Department of Preventive and Public Health Dentistry, College of Dentistry, Wonkwang University, Iksan, Korea. smagn@wonkwang.ac.kr
  • 2Institute of Wonkwang Dental Research, Wonkwang University, Iksan, Korea.

Abstract


OBJECTIVES
The purpose of this study was to evaluate the prediction validity of the caries activity test with a sulfisomidine mixture (SAHS test).
METHODS
This longitudinal follow-up study was conducted for 3 years. The subjects were 155 elementary schoolchildren. Oral examination was performed by examining each tooth surface of the subjects. The number of teeth with new caries lesions was calculated by comparing between the baseline data of the initial oral examination and the results of the second oral examination performed after 3 years. The Dentocult SM test was used as the reference in the analysis of the caries prediction validity of the SAHS test. The items of the validity test for carries prediction were as follows: sensitivity, specificity, predictive value, and likelihood ratio.
RESULTS
The correlation between new caries lesions and the SAHS test scores was greater than that between new caries lesions and the Dentocult SM test scores. The receiver-operating analysis revealed that the area under the curve of the SAHS test was higher than that of the Dentocult SM test. The caries prediction validity of the SAHS test (grade 12) was as follows: sensitivity, 0.71-0.70; specificity, 0.60-0.58; positive predictive value, 0.79-0.78; negative predictive value, 0.49 (screening criterion 5). The SAHS test scores were similar to or higher than the scores in the items of the Dentocult SM test.
CONCLUSIONS
The SAHS test is considered useful for clinical applications.

Keyword

Children; Dental caries; Dental caries activity tests; Prediction; ROC curve

MeSH Terms

Child
Dental Caries
Dental Caries Activity Tests
Diagnosis, Oral
Follow-Up Studies*
Humans
ROC Curve
Sensitivity and Specificity
Sulfisomidine*
Tooth
Sulfisomidine

Figure

  • Fig. 1. ROC curve by Dentocult SM test and Sulfisomidine test (grade 12, 4).


Reference

References

1. Hamada S, Slade HD. Biology, immunology, and cariogenicity of streptococcus mutans. Microbiol Rev. 1980; 44:331–384.
Article
2. Park DI, Kim HD, Jin BH, Park YD, Shin SC, Cho JW, et al. Caries activity test. Clinical Preventive Dentistry. 5th ed.Korea: Komoonsa;2012. p. 265–278.
3. Snyder ML. A simple colorimetric method for the estimation of relative numbers of lactobacilli in the saliva. J Dent Res. 1940; 19:349–355.
Article
4. Shimono T. A new colorimetric caries activity test. Dent Outlook. 1974; 43:829–835.
5. Jordan HV, Laraway R, Snirch R, Marmel M. A simplified diagnostic system for cultural detection and enumeration of streptococcus mutans. J Dent Res. 1987; 66:57–61.
Article
6. Jensen B, Bratthall D. A new method for the estimation of mutans streptococci in human saliva. J Dent Res. 1989; 68:468–471.
Article
7. Oh YB, Lee HS, Kim SN. Correlation between caries experience and caries activity test score by sulfisomidine containing acidic high sucrose liquid medium in primary school children. J Korean Acad Oral Health. 1992; 16:41–52.
8. Kim SJ, Lee KH. Comparative study of the inhibitory effect of bacitracin and sulphisomidine in plaque culture test of preschool children with sucrose liquid medium. J Korean Acad Pediatr Dent. 1991; 18:44–50.
9. Kim YJ, Lee KH. Correlation between dmfs index and caries activity test scores with high-sucrose medium in preschool children. J Korean Acad Pediatr Dent. 1991; 18:51–57.
10. Park SH, Lee HS, Lee SH. Validity of caries prediction by caries activity tests using sulfisomidine-containing acidic high sucrose liquid medium. J Korean Acad Oral Health. 2014; 38:138–147.
Article
11. Nishimura M, Oda T, Kariya N, Matsumura S, Shimono T. Using a caries activity test to predict caries risk in early childhood. J Am Dent Assoc. 2008; 139:63–71.
Article
12. Gábris K, Nagy G, Madléna M, Dénes Z, Márton S, Keszthelyi G, et al. Associations between microbiological and salivary caries activity tests and caries experience in hungarian adolescents. Caries Res. 1999; 33:191–195.
13. Seki M, Karakama F, Yamashita Y. Does a clinical evaluation of oral cleanliness correlate with caries incidence in preschool children? findings from a cohort study. J Oral Sci. 2003; 45:93–98.
Article
14. Lee SH, Lee NY. A study on the caries activity test with visible light induced by laser. J Korean Acad Pediatr Dent. 2000; 27:161–168.
15. Pannu P, Gambhir R, Sujlana A. Correlation between the salivary streptococcus mutans levels and dental caries experience in adult population of Chandigarh, India. Eur J Dent. 2013; 7:191–195.
Article
16. Swets JA. Measuring the accuracy of diagnostic systems. Science. 1988; 240:1285–1293.
Article
17. Petersson GH, Isberg PE, Twetman S. Caries risk assessment in school children using a reduced cariogram model without saliva tests. BMC Oral Health. 2010; 10:5–10.
Article
18. Campus G, Cagetti MG, Sale S, Carta G, Lingström P. Cariogram validity in schoolchildren: a two-year follow-up study. Caries Res. 2012; 46:16–22.
Article
19. Gao XL, Hsu CY, Xu Y, Hwarng HB, Loh T, Koh D. Building caries risk assessment models for children. J Dent Res. 2010; 89:637–643.
Article
20. Holbrook WP, de Soet JJ, de Graaff J. Prediction of dental caries in pre-school children. Caries Res. 1993; 27:424–430.
Article
21. Tagliaferro EP, Pereira AC, Meneghim Mde C, Ambrosano GM. Assessment of dental caries predictors in a seven-year longitudinal study. J Public Health Dent. 2006; 66:169–173.
Article
22. Splieth C, Bernhardt O. Prediction of caries development for molar fissures with semiquantitative mutans streptococci test. Eur J Oral Sci. 1999; 107:164–169.
Full Text Links
  • JKAOH
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr