Clin Mol Hepatol.  2015 Sep;21(3):200-211. 10.3350/cmh.2015.21.3.200.

Personalized management of cirrhosis by non-invasive tests of liver fibrosis

Affiliations
  • 1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong. wongv@cuhk.edu.hk
  • 2State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.

Abstract

Owing to the high prevalence of various chronic liver diseases, cirrhosis is one of the leading causes of morbidity and mortality worldwide. In recent years, the development of non-invasive tests of fibrosis allows accurate diagnosis of cirrhosis and reduces the need for liver biopsy. In this review, we discuss the application of these non-invasive tests beyond the diagnosis of cirrhosis. In particular, their role in the selection of patients for hepatocellular carcinoma surveillance and varices screening is highlighted.

Keyword

Transient elastography; FibroScan; FibroTest; Hepatocellular carcinoma; Varices

MeSH Terms

Biomarkers/blood
Carcinoma, Hepatocellular/diagnosis
*Elasticity Imaging Techniques
Endoscopy, Digestive System
Humans
Hypertension, Portal/complications
Liver Cirrhosis/complications/*diagnosis
Liver Neoplasms/diagnosis
Risk Factors
Biomarkers
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