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Hepatic venous pressure gradient: clinical use in chronic liver disease

Suk KT

Portal hypertension is a severe consequence of chronic liver diseases and is responsible for the main clinical complications of liver cirrhosis. Hepatic venous pressure gradient (HVPG) measurement is the best...
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Deficiencies in proteins C and S in a patient with idiopathic portal hypertension accompanied by portal vein thrombosis

Hwang S, Kim DY, Kim M, Chon YE, Lee HJ, Park YN, Park JY, Ahn SH, Han KH, Chon CY

Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have...
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A Case of Klippel-Trenaunay-Weber Syndrome Presenting with Esophageal and Gastric Varices Bleeding

Kim JH, Kim CW, Son DK, Chung BW, Yang SE, Kim JI, Kim JK, Chung IS

  • KMID: 772619
  • Korean J Gastroenterol.
  • 2004 Feb;43(2):137-141.
Klippel-Trenaunay-Weber syndrome is a congenital vascular disorder consisted of a variety of vascular malformations, enlargement of the involved limb, and varicose veins. We report a case of Klippel-Trenaunay-Weber syndrome presenting...
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The lymphatic vascular system in liver diseases: its role in ascites formation

Chung C, Iwakiri Y

The lymphatic system is part of the circulatory system and plays a key role in normal vascular function. Its failure plays a crucial role in the development and maintenance of...
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Endoscopic Findings and Clinical Significance of Portal Hypertensive Colopathy

Jeong IB, Lee TH, Lim SM, Ryu KH, Kim YS, Kim SM, Im EH, Huh KC, Choi YW, Kang YW

BACKGROUND/AIMS: The endoscopic findings and clinical relevance of portal hypertensive colopathy are not well described in Korea. We aimed to do a retrospective study of mucosal changes in the colon...
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Hepatoportal Sclerosis in Childhood: Descriptive Analysis of 12 Patients

Cantez MS, Gerenli N, Ertekin V, Gulluoglu , Durmaz O

Hepatoportal sclerosis (HPS) is defined as sclerosis of portal areas in the absence of cirrhosis. There is little information about HPS in children in the literature. The aim of this...
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Relationship between Tetrahydrobiopterin and Portal Hypertension in Patients with Chronic Liver Disease

Hong WK, Shim KY, Baik SK, Kim MY, Cho MY, Jang YO, Park YS, Han J, Kim G, Cho YZ, Hwang HW, Lee JH, Chae MH, Kwon SO

Tetrahydrobiopterin (BH4) is an essential cofactor in NO synthesis by endothelial nitric oxide synthase (eNOS) enzymes. It has been previously suggested that reduced intrahepatic BH4 results in a decrease in...
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An Analysis of Extravariceal Collaterals of Gastric Varices Using Magnetic Resonance Angiography in Portal Hypertensive Patients

Park CH, Chun HJ, Jeong RS, Kim KH, Kim YS, Kim YS, Jeen YT, Lee HS, Um SH, Lee SW, Choi JH, Kim CD, Ryu HS, Hyun JH

  • KMID: 772562
  • Korean J Gastroenterol.
  • 2003 Oct;42(4):313-321.
BACKGROUND/AIMS: This study was aimed to analyze the relationship between gastric varices and its collaterals using magnetic resonance angiography (MRA) and to assess the usefulness of MRA in studies of...
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Clinical Results of the Transjugular Intrahepatic Portosystemic Shunt (TIPS) for the Treatment of Variceal Bleeding

Han SW, Joo YE, Kim HS, Choi SK, Rew JS, Kim JK, Kim SJ

  • KMID: 759516
  • Korean J Intern Med.
  • 2000 Dec;15(3):179-186.
BACKGROUND: Transjugular intrahepatic portosystemic shunt (TIPS) has been popularized for the treatment of refractory variceal bleeding. The aim of this study was to assess the safety and long-term effect of...
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Effects of candesartan and propranolol combination therapy versus propranolol monotherapy in reducing portal hypertension

Kim JH, Kim JM, Cho YZ, Na JH, Kim HS, Kim HA, Kang HW, Baik SK, Kwon SO, Cha SH, Kim YJ, Kim MY

BACKGROUND/AIMS: Angiotensin receptor blockers (ARBs) inhibit activated hepatic stellate cell contraction and are thought to reduce the dynamic portion of intrahepatic resistance. This study compared the effects of combined treatment...
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The Risk Factors for Bleeding of Fundal Varices in Patients with Liver Cirrhosis

Park EJ, Jang JY, Lee JE, Jeong SW, Lee SH, Kim SG, Cha SW, Kim YS, Cho YD, Cho JY, Kim HS, Kim BS, Kim YJ

  • KMID: 1712331
  • Gut Liver.
  • 2013 Nov;7(6):704-711.
BACKGROUND/AIMS: The relationship between portal hemodynamics and fundal varices has not been well documented. The purpose of this study was to understand the pathophysiology of fundal varices and to investigate...
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Measurement of hepatic venous pressure gradient in liver cirrhosis: Relationship with the status of cirrhosis, varices, and ascites in Korea

Kim MY, Baik SK, Suk KT, Yea CJ, Lee IY, Kim JW, Cha SH, Kim YJ, Um SH, Han KH

BACKGROUND/AIMS: The relationships between the hepatic venous pressure gradient (HVPG) and the status of cirrhosis, complications of portal hypertension and the severity of cirrhosis are not clear. The aim...
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Plug-Assisted Retrograde Transvenous Obliteration for the Treatment of Gastric Variceal Hemorrhage

Chang MY, Kim MD, Kim T, Shin W, Shin M, Kim GM, Won JY, Park SI, Lee DY

OBJECTIVE: To evaluate the feasibility, safety, and clinical outcomes of plug-assisted retrograde transvenous obliteration (PARTO) to treat gastric variceal hemorrhage in patients with portal hypertension. MATERIALS AND METHODS: From May 2012...
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A clinical predictor of varices and portal hypertensive gastropathy in patients with chronic liver disease

Min YW, Bae SY, Gwak GY, Paik YH, Choi MS, Lee JH, Paik SW, Yoo BC, Koh KC

BACKGROUND/AIMS: The aim of this study was to identify the parameters that could noninvasively predict the presence of esophageal/gastric varices and portal hypertensive gastropathy (PHG) in patients with chronic liver...
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis

Wong GL, Espinosa W, Wong VW

Owing to the high prevalence of various chronic liver diseases, cirrhosis is one of the leading causes of morbidity and mortality worldwide. In recent years, the development of non-invasive tests...
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What we need to know when performing and interpreting US elastography

Park SH, Kim SY, Suh CH, Lee SS, Kim KW, Lee SJ, Lee MG

According to the increasing need for accurate staging of hepatic fibrosis, the ultrasound (US) elastography techniques have evolved significantly over the past two decades. Currently, US elastography is increasingly used...
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