J Periodontal Implant Sci.  2016 Aug;46(4):266-276. 10.5051/jpis.2016.46.4.266.

Risk indicators related to peri-implant disease: an observational retrospective cohort study

Affiliations
  • 1Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, IRCCS Cà Granda Foundation Maggiore Policlinico Hospital, University of Milan, Milan, Italy. pierpaolo.poli@unimi.it

Abstract

PURPOSE
The aim of the present study was to retrospectively investigate the influence of potential risk indicators on the development of peri-implant disease.
METHODS
Overall, 103 patients referred for implant treatment from 2000 to 2012 were randomly enrolled. The study sample consisted of 421 conventional-length (>6 mm) non-turned titanium implants that were evaluated clinically and radiographically according to pre-established clinical and patient-related parameters by a single investigator. A non-parametric Mann-Whitney U test or Kruskal-Wallis rank test and a logistic regression model were used for the statistical analysis of the recorded data at the implant level.
RESULTS
The diagnosis of peri-implant mucositis and peri-implantitis was made for 173 (41.1%) and 19 (4.5%) implants, respectively. Age (≥65 years), patient adherence (professional hygiene recalls <2/year) and the presence of plaque were associated with higher peri-implant probing-depth values and bleeding-on-probing scores. The logistic regression analysis indicated that age (P=0.001), patient adherence (P=0.03), the absence of keratinized tissue (P=0.03), implants placed in pristine bone (P=0.04), and the presence of peri-implant soft-tissue recession (P=0.000) were strongly associated with the event of peri-implantitis.
CONCLUSIONS
Within the limitations of this study, patients aged ≥65 years and non-adherent subjects were more prone to develop peri-implant disease. Therefore, early diagnosis and a systematic maintenance-care program are essential for maintaining peri-implant tissue health, especially in older patients.

Keyword

Dental implants; Implant-supported dental prosthesis; Periodontal diseases; Peri-implantitis; Retrospective study; Risk factors

MeSH Terms

Cohort Studies*
Dental Implants
Dental Prosthesis, Implant-Supported
Diagnosis
Early Diagnosis
Humans
Hygiene
Logistic Models
Mucositis
Patient Compliance
Peri-Implantitis
Periodontal Diseases
Research Personnel
Retrospective Studies*
Risk Factors
Titanium
Dental Implants
Titanium

Reference

1. Albrektsson T, Isidor F. In : Lang NP, Karring T, editors. Consensus report of session IV. Proceedings of the First European Workshop on Periodontology; London: Quintessence;1994. p. 365–369.
2. Lindhe J, Meyle J; Group D of European Workshop on Periodontology. Peri-implant diseases: Consensus Report of the Sixth European Workshop on Periodontology. J Clin Periodontol. 2008; 35:Suppl. 282–285.
Article
3. Peri-implant mucositis and peri-implantitis: a current understanding of their diagnoses and clinical implications. J Periodontol. 2013; 84:436–443.
4. Lang NP, Berglundh T; Working Group 4 of Seventh European Workshop on Periodontology. Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology. J Clin Periodontol. 2011; 38:Suppl 11. 178–181.
Article
5. Sanz M, Chapple IL; Working Group 4 of the VIII European Workshop on Periodontology. Clinical research on peri-implant diseases: consensus report of Working Group 4. J Clin Periodontol. 2012; 39:Suppl 12. 202–206.
Article
6. Mombelli A, Müller N, Cionca N. The epidemiology of peri-implantitis. Clin Oral Implants Res. 2012; 23:Suppl 6. 67–76.
Article
7. Heitz-Mayfield LJ. Peri-implant diseases: diagnosis and risk indicators. J Clin Periodontol. 2008; 35:Suppl. 292–304.
Article
8. Schwarz F, Becker K, Sahm N, Horstkemper T, Rousi K, Becker J. The prevalence of peri-implant diseases for two-piece implants with an internal tube-in-tube connection: a cross-sectional analysis of 512 implants. Clin Oral Implants Res. Forthcoming 2015.
Article
9. Konstantinidis IK, Kotsakis GA, Gerdes S, Walter MH. Cross-sectional study on the prevalence and risk indicators of peri-implant diseases. Eur J Oral Implantology. 2015; 8:75–88.
10. Turri A, Rossetti PH, Canullo L, Grusovin MG, Dahlin C. Prevalence of peri-implantitis in medically compromised patients and smokers: a systematic review. Int J Oral Maxillofac Implants. 2016; 31:111–118.
Article
11. Dalago HR, Schuldt Filho G, Rodrigues MA, Renvert S, Bianchini MA. Risk indicators for Peri-implantitis. A cross-sectional study with 916 implants. Clin Oral Implants Res. Forthcoming 2016.
12. Consensus report. Periodontal diseases: epidemiology and diagnosis. Ann Periodontol. 1996; 1:216–222.
13. Koldsland OC, Scheie AA, Aass AM. The association between selected risk indicators and severity of peri-implantitis using mixed model analyses. J Clin Periodontol. 2011; 38:285–292.
Article
14. Ferreira SD, Silva GL, Cortelli JR, Costa JE, Costa FO. Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol. 2006; 33:929–935.
Article
15. Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015; 42:Suppl 16. S158–71.
Article
16. Atieh MA, Alsabeeha NH, Faggion CM Jr, Duncan WJ. The frequency of peri-implant diseases: a systematic review and meta-analysis. J Periodontol. 2013; 84:1586–1598.
Article
17. Marrone A, Lasserre J, Bercy P, Brecx MC. Prevalence and risk factors for peri-implant disease in Belgian adults. Clin Oral Implants Res. 2013; 24:934–940.
Article
18. Trullenque-Eriksson A, Guisado Moya B. Retrospective long-term evaluation of dental implants in totally and partially edentulous patients: part II: periimplant disease. Implant Dent. 2015; 24:217–221.
19. Muller F. Too old for implants? Risks and benefits in elderly patients. Forum Implantol. 2009; 5:107–111.
20. Renvert S, Aghazadeh A, Hallström H, Persson GR. Factors related to peri-implantitis - a retrospective study. Clin Oral Implants Res. 2014; 25:522–529.
21. Park JC, Baek WS, Choi SH, Cho KS, Jung UW. Long-term outcomes of dental implants placed in elderly patients: a retrospective clinical and radiographic analysis. Clin Oral Implants Res. Forthcoming 2016.
Article
22. Serino G, Ström C. Peri-implantitis in partially edentulous patients: association with inadequate plaque control. Clin Oral Implants Res. 2009; 20:169–174.
Article
23. Vervaeke S, Collaert B, Cosyn J, Deschepper E, De Bruyn H. A multifactorial analysis to identify predictors of implant failure and peri-implant bone loss. Clin Implant Dent Relat Res. 2015; 17:Suppl 1. e298–307.
Article
24. Costa FO, Takenaka-Martinez S, Cota LO, Ferreira SD, Silva GL, Costa JE. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012; 39:173–181.
Article
25. Smeets R, Henningsen A, Jung O, Heiland M, Hammächer C, Stein JM. Definition, etiology, prevention and treatment of peri-implantitis--a review. Head Face Med. 2014; 10:34.
26. Saaby M, Karring E, Schou S, Isidor F. Factors influencing severity of peri-implantitis. Clin Oral Implants Res. 2016; 27:7–12.
Article
27. Brito C, Tenenbaum HC, Wong BK, Schmitt C, Nogueira-Filho G. Is keratinized mucosa indispensable to maintain peri-implant health? A systematic review of the literature. J Biomed Mater Res B Appl Biomater. 2014; 102:643–650.
Article
28. Chen ST, Darby IB, Reynolds EC, Clement JG. Immediate implant placement postextraction without flap elevation. J Periodontol. 2009; 80:163–172.
Article
29. Maynard JG Jr, Wilson RD. Physiologic dimensions of the periodontium significant to the restorative dentist. J Periodontol. 1979; 50:170–174.
Article
30. Thoma DS, Mühlemann S, Jung RE. Critical soft-tissue dimensions with dental implants and treatment concepts. Periodontol 2000. 2014; 66:106–118.
Article
31. Kan JY, Rungcharassaeng K, Umezu K, Kois JC. Dimensions of peri-implant mucosa: an evaluation of maxillary anterior single implants in humans. J Periodontol. 2003; 74:557–562.
Article
32. Linkevicius T, Apse P, Grybauskas S, Puisys A. The influence of soft tissue thickness on crestal bone changes around implants: a 1-year prospective controlled clinical trial. Int J Oral Maxillofac Implants. 2009; 24:712–719.
33. Teughels W, Van Assche N, Sliepen I, Quirynen M. Effect of material characteristics and/or surface topography on biofilm development. Clin Oral Implants Res. 2006; 17:Suppl 2. 68–81.
Article
34. Zetterqvist L, Feldman S, Rotter B, Vincenzi G, Wennström JL, Chierico A, et al. A prospective, multicenter, randomized-controlled 5-year study of hybrid and fully etched implants for the incidence of peri-implantitis. J Periodontol. 2010; 81:493–501.
Article
35. Schmidlin PR, Müller P, Attin T, Wieland M, Hofer D, Guggenheim B. Polyspecies biofilm formation on implant surfaces with different surface characteristics. J Appl Oral Sci. 2013; 21:48–55.
Article
36. Albouy JP, Abrahamsson I, Berglundh T. Spontaneous progression of experimental peri-implantitis at implants with different surface characteristics: an experimental study in dogs. J Clin Periodontol. 2012; 39:182–187.
Article
37. Renvert S, Polyzois I, Claffey N. How do implant surface characteristics influence peri-implant disease? J Clin Periodontol. 2011; 38:Suppl 11. 214–222.
Article
38. Karbach J, Callaway A, Kwon YD, d’Hoedt B, Al-Nawas B. Comparison of five parameters as risk factors for peri-mucositis. Int J Oral Maxillofac Implants. 2009; 24:491–496.
39. Busenlechner D, Fürhauser R, Haas R, Watzek G, Mailath G, Pommer B. Long-term implant success at the Academy for Oral Implantology: 8-year follow-up and risk factor analysis. J Periodontal Implant Sci. 2014; 44:102–108.
Article
Full Text Links
  • JPIS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr