J Pathol Transl Med.  2016 Jul;50(4):306-308. 10.4132/jptm.2015.11.15.

Intramuscular Tenosynovial Giant Cell Tumor, Diffuse-Type

• Lee YJ
• Kang Y
• Jung J
• Kim S
• Kim CH

• KMID: 2345554
• DOI: http://doi.org/10.4132/jptm.2015.11.15

Abstract

No abstract available.

MeSH Terms

Giant Cell Tumors*
Giant Cells*

Figure

• 

  Fig. 1. (A) T2-weighted magnetic resonance image showing a well-marginated mass in the muscle of the right thigh (arrow). (B) The cut surface of the resected specimen shows a variegated brown to yellow colored mass with multifocal dark reddish punctuate areas and focal myxoid portions.

• 

  Fig. 2. (A) Hematoxylin-eosin stained slide of a diffuse-type tenosynovial giant cell tumor shows sheets of small histiocytes with a villonodular pattern and hemosiderin pigments. (B) Variable proportions of polygonal mononuclear cells and multinucleated giant cell are seen. (C) The tumor cells are positive for CD68 immunohistochemical staining. (D) Nested polymerase chain reaction to detect the COL6A3-CSF1 fusion transcript (lane 1 and lane 2) and CSF1 wild-type transcripts (lane 3). COL6A3, collagen type VI alpha-3; CSF1, colony stimulating factor-1; NC, negative control; L, ladder.

Reference

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