A clinical study on relationship between thyrogram and hepatogram using the radioactive I-131

Lee, N J; Suh, W H; Ahn, K S; Lee, M J

Abstract

Throughout the known various tests for each thyroid states, there is no complete informative method forevaluating thyroid function. In an attempt to evaluating the thyroidal & hepatic gross dynamic and relationship ofthem, the author and made an observation on 20 minutes uptake curve of oral Iodine-131 by the thyroid gland andliver in addition to the several usual thyroid evaluating tests following administration of 50 micron CiIodine-131 in 37 cases of euthyriodism, 30 cases of hyperthyroidism, and 5 cases of hypothyroidism. The resultsobtained are summerized as follows; 1. The early uptake curve of thyrogram obtained immediately after giving anoral dose of Iodine-131 revealed relatively steep elevation in hyperthyroidism and less steep or stable elevationin hypothyroidism. The mean inclination of uptake curves was 23.3±8.7degrees in euthyroidism, 51.6±14.3degreesin hyperthyroidism, 9.3±3.9degrees in hypothyroidism, The inclination of this increasing uptake curve reflectedwell the functional status of thyroid gland. 2. On the relationship between obtained thyrogram and hepatogram ofinclination & declination, the thyrogram is described exponential curve of gradual inclination followed by gradualdeclination curve of hepatogram. Rapid inclination curve is noticed in hyperthyroidism, while delayed inclinationin hypothyroidism. 3. Gastrointestinal motility study of barium meal, is shown increased motility inhyperthyroidism and decreaased motility in hypothyroidism. The functional relationship between thryoidal & hepaticuptake rate and gastrointestinal motility must be evaluted by further study.