An experimental microangiographic study on radiation injury

Han, M C; Kim, C W; Yeon, K M; Yoo, S Y; Chang, K H

Abstract

Microangiography may be defined as a branch of radiology which deals with the production and study ofroentgenograms of thin sections of tissue for evaluation of microvasculatures. Its main advantage is that itpermits study of a vascular system in continuity so that the pattern and overall architecture can be appreciated.Authors performed the micorangiography to study the irradiation changes of kidney in 30 rabbits. Following localirradition of 2000 rads to one kidney of each rabbit, both normal and irradiated kidneys of each rabbit werestudied. The results area as follows; 1. In the normal kidneys there is good filling of interlobular arteries,afferent arterioles, glomeruli and efferent arterioles. 2. In the early stage (1 month) after irradiation thereappears to be no identifiable abnormal findings except slightly poor filling of glomeruli in the irradiatedkidneys. 3. 5 months after irradiation the ratiation-injured kidneys reveal intense curling and spralling ofinterlobular arteries and afferent arterioles with poor filling of glomeruli. 4. Microangiogarhy, as expected,proved to be of great value in evaluation of the microvasculature of the kidney.