J Korean Dent Soc Anesthesiol.  2012 Dec;12(4):223-227. 10.17245/jkdsa.2012.12.4.223.

Use of Midazolam Intranasal Spray for Dental Treatment of Autism Patients

• Song YG
• Lee SY
• Kim SO

• KMID: 2345036
• DOI: http://doi.org/10.17245/jkdsa.2012.12.4.223

Abstract

Autism patients in general have bad oral hygiene. It is hard for autism patients to get dental treatment as poor communication. Therefore, they may have to be treated by deep sedation or general anesthesia in numerous cases. However, this process requires induction with mask, so it is not easy to do for disobliging autism patient. Midazolam is a water-soluble benzodiazepine, has been used in pediatric dentistry or dentistry for the handicapped because of rapid onset. Midazolam can be administered through oral, rectal, intramuscular,intravenous, and intranasal (IN) routes. IN route of midazolam may be considered as effective way to allay for uncooperative autism patients before general anesthesia. In this case report, two autism patients required dental treatment. Intranasal spray of midazolam before general anesthesia was safe and effective procedure of behavioral management.

Keyword

Intranasal spray; Midazolam

MeSH Terms

Anesthesia, General
Autistic Disorder*
Benzodiazepines
Deep Sedation
Dentistry
Disabled Persons
Humans
Masks
Midazolam*
Oral Hygiene
Pediatric Dentistry
Benzodiazepines
Midazolam