Korean Circ J.  2016 May;46(3):421-424. 10.4070/kcj.2016.46.3.421.

Reversal of Pacing-Induced Cardiomyopathy by Normal QRS Axis Pacing

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. oys@catholic.ac.kr

Abstract

Right ventricular apical pacing has been a commonly used method for placement of permanent pacemaker, but it is known to be associated with ventricular dyssynchrony and may lead to heart failure. Septal pacing could be an alternative method to improve this complication but the results have been conflicting; hence, other strategies are needed. This case is about a patient with pacing-induced cardiomyopathy who showed much improvement after repositioning the leads to a site different from that of normally paced QRS axis.

Keyword

Pacemaker; Heart failure; Cardiac pacing; Cardiomyopathy

MeSH Terms

Cardiomyopathies*
Heart Failure
Humans
Methods

Figure

  • Fig. 1 Radiographic changes of the patient before and after normal QRS axis pacing. (A) Initial chest X-ray at admission shows implanted pacemaker with marked cardiomegaly. (B) Chest X-ray of the patient immediate post lead repositioning with resultant right ventricular lead placed in septum. (C) Chest X-ray of the patient 1 year after normal QRS axis pacing showing significant improvement of cardiomegaly.

  • Fig. 2 Electrocardiogram (ECG) changes of the patient before and after normal QRS axis pacing. The QRS duration was 144, 138, and 96 ms at admission, immediate post lead repositioning, and 6 months later, respectively. (A) Initial ECG at admission showing abnormal QRS axis. (B) ECG of the patient immediately after post lead repositioning to achieve normally paced QRS axis. (C) ECG of the patient 6 months after the lead repositioning.


Cited by  1 articles

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Hye Bin Gwag, Kwang Jin Chun, Jin Kyung Hwang, Kyoung-Min Park, Young Keun On, June Soo Kim, Seung-Jung Park
Yonsei Med J. 2017;58(4):703-709.    doi: 10.3349/ymj.2017.58.4.703.


Reference

1. Tse HF, Yu C, Wong KK, et al. Functional abnormalities in patients with permanent right ventricular pacing: the effect of sites of electrical stimulation. J Am Coll Cardiol. 2002; 40:1451–1458.
2. Sweeney MO, Hellkamp AS, Ellenbogen KA, et al. Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction. Circulation. 2003; 107:2932–2937.
3. Thackray SD, Witte KK, Nikitin NP, Clark AL, Kaye GC, Cleland JG. The prevalence of heart failure and asymptomatic left ventricular systolic dysfunction in a typical regional pacemaker population. Eur Heart J. 2003; 24:1143–1152.
4. Sweeney MO, Hellkamp AS. Heart failure during cardiac pacing. Circulation. 2006; 113:2082–2088.
5. Lieberman R, Padeletti L, Schreuder J, et al. Ventricular pacing lead location alters systemic hemodynamics and left ventricular function in patients with and without reduced ejection fraction. J Am Coll Cardiol. 2006; 48:1634–1641.
6. Yu CM, Chan JY, Zhang Q, et al. Biventricular pacing in patients with bradycardia and normal ejection fraction. N Engl J Med. 2009; 361:2123–2134.
7. Kim SH, Oh YS, Nam GB, et al. Paced QRS axis as a predictor of pacing-induced left ventricular dysfunction. J Interv Card Electrophysiol. 2014; 41:223–229.
8. Dreger H, Maethner K, Bondke H, Baumann G, Melzer C. Pacing-induced cardiomyopathy in patients with right ventricular stimulation for >15 years. Europace. 2012; 14:238–242.
9. Te CC, Stavrakis S, Lozano P, Reynolds D. Apparent acute reversible right ventricular pacing-induced left ventricular dysfunction. J Cardiovasc Electrophysiol. 2013; 24:224–226.
10. Fung JW, Zhang Q, Yip GW, Yu CM. Reversible left ventricular dyssynchrony and heart failure induced by right ventricular pacing. Int J Cardiol. 2009; 134:117–119.
11. Vanagt WY, Prinzen FW, Delhaas T. Reversal of pacing-induced heart failure by left ventricular apical pacing. N Engl J Med. 2007; 357:2637–2638.
12. Ouali S, Azzez S, Kacem S, et al. Acute left ventricular dysfunction secondary to right ventricular septal pacing in a woman with initial preserved contractility: a case report. J Med Case Rep. 2011; 5:524.
13. Victor F, Leclercq C, Mabo P, et al. Optimal right ventricular pacing site in chronically implanted patients: a prospective randomized crossover comparison of apical and outflow tract pacing. J Am Coll Cardiol. 1999; 33:311–316.
14. Stambler BS, Ellenbogen K, Zhang X, et al. Right ventricular outflow versus apical pacing in pacemaker patients with congestive heart failure and atrial fibrillation. J Cardiovasc Electrophysiol. 2003; 14:1180–1186.
15. Cano O, Osca J, Sancho-Tello MJ, et al. Comparison of effectiveness of right ventricular septal pacing versus right ventricular apical pacing. Am J Cardiol. 2010; 105:1426–1432.
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