J Korean Neurol Assoc.
2014 Nov;32(4):275-278. 10.0000/jkna.2014.32.4.275.
Oculopharyngeal Palsy in Patients with Coexistence of Anti-GQ1b and GT1a Antibodies
- Affiliations
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- 1Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yepark407@gmail.com
- 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
- 3Department of Neurology, College of Medicine, Dong-A University, Busan, Korea.
- KMID: 2343552
- DOI: http://doi.org/10.0000/jkna.2014.32.4.275
Abstract
- The presence of antiganglioside antibodies is closely associated with the clinical characteristics of Guillain-Barre syndrome (GBS), as evidenced by the presence of anti-GQ1b antibody in Miller-Fisher syndrome and anti-GT1a antibody in a pharyngeal-cervical-brachial variant of GBS. We report herein three patients harboring both anti-GT1a and anti-GQ1b antibodies who all exhibited oculopharyngeal palsy and additional features of ataxia, facial palsy, internal ophthalmoplegia, and visual disturbance. The findings of this study suggest that oculopharyngeal palsy is a common clinical manifestation determined by the coexistence of anti-GQ1b and GT1a antibodies.
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