J Korean Neurol Assoc.
2010 Nov;28(4):291-294.
Guillain-Barre Syndrome With Antibody to Ganglioside GT1a
- Affiliations
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- 1Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yeun0407@yahoo.co.kr
- 2Department of Neurology, Dong-A University Medical Center, Busan, Korea.
Abstract
- The presence of serum antibodies to various gangliosides, such as anti-GQ1b, is closely related to the clinical features of Guillain-Barre syndrome. However, the phenotype associated with anti-GT1a IgG has not yet been determined, although it has been detected in some cases of the pharyngeal-cervical-brachial variant. We report herein two patients harboring anti-GT1a IgG who both presented with profound dyspnea, dysphagia, and quadriparesis. The findings of this report suggest that the anti-GT1a antibody specifies a clinical feature of oropharyngeal palsy.
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