J Korean Neurol Assoc.
2008 Feb;26(1):73-77.
Pisa Syndrome in a Patient with Alzheimer's Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report
- Affiliations
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- 1Department of Neurology, School of Medicine, Catholic University of Daegu, Daegu, Korea. dolbaeke@cu.ac.kr
Abstract
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Extrapyramidal symptoms are common in patients with advanced Alzheimer's disease and have various etiologies. We report a 65-year-old man with probable Alzheimer's disease (AD) who concomitantly developed Pisa syndrome, ataxic gait, postural instability and voiding difficulty. Pisa syndrome improved after the discontinuation of acetylcholinesterase inhibitor (AchEI) and antipsychotics. However his ataxic gait and voiding symptoms persisted. A ventriculo-peritoneal shunt operation eliminated the symptoms except for cognition. We report Pisa syndrome in a patient with Alzheimer's disease and concomitant normal pressure hydrocephalus.