J Korean Neurol Assoc.  2004 Dec;22(6):666-669.

A Case of Neurosyphilis Radiologically Mimicking Herpes Simplex Encephalitis

Affiliations
  • 1Department of Neurology, Inje University College of Medicine, Busan, Korea. jsk120@hanmail.net

Abstract

The neuroradiologic findings of neurosyphilis are variable. A 36-year-old man was admitted due to gradually progressing abnormal behavior and personality change. The brain MRI revealed bilateral mesiotemporal hyperintensity on FLAIR and T2 weighted MR images. Analysis of serum and CSF demonstrated the presence of antibodies to Treponema pallidum. The patient was treated with penicillin, and he had clinical improvements. Neurosyphilis can manifest with MR imaging abnormalities similar to those of herpes encephalitis.

Keyword

Neurosyphilis; Magnetic resonance imaging; Herpes simplex encephalitis

MeSH Terms

Adult
Antibodies
Brain
Encephalitis, Herpes Simplex*
Herpes Simplex*
Humans
Magnetic Resonance Imaging
Neurosyphilis*
Penicillins
Treponema pallidum
Antibodies
Penicillins
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