J Korean Neurol Assoc.
2003 Apr;21(2):207-209.
Oxytocin-induced Water Intoxication with Seizures and Altered Mental State
- Affiliations
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- 1Department of Neurology, Kangnung Asan Hospital, University of Ulsan College of Medicine, 415 Bangdong-ri, Sacheon-myon, Kangnung, Gangwon-do, 210-850, Korea. jkd@knh.co.kr
- 2Department of Family medicine, Seoul Asan Hospital, Asan Medical center, University of Ulsan College of Medicine, Korea.
Abstract
- Water intoxication associated with hyponatremia is a rare and sometimes fatal complication of oxytocin. We report a 18-year-old primigravida who presented with vomiting, seizures, and stuporous mental state after abortion with oxytocin infusion. The serum sodium was 116 mEq/L and serum osmolality was 234 mosm/kg. The serum sodium level as well as clinical symptoms were improved after hypertonic saline infusion. We suggest that the serum electrolytes and osmolarity should be examined in patients who presenting with seizure and altered mental state with history of labour or abortion.
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