J Korean Neurol Assoc.  2002 May;20(3):307-310.

A Case of Chronic Methyl Bromide Poisoning Associated with Cerebellar Ataxia, Polyneuropathy and Optic Neuropathy

Affiliations
  • 1Department of Neurology, School of Medicine, Pusan National University, Korea. dskim@pusan.ac.kr
  • 2Department of Preventive and Occupational Medicine, School of Medicine, Pusan National University, Korea.
  • 3Center for Occupational Epidemiology and Surveillance, Korea.

Abstract

Methyl bromide is a commonly used fumigant to disinfect soil, grains, and warehouses. The accumulation of danger-ous concentrations can produce various neurotoxic effects in humans. A 45-year-old man, who had worked in the fumi-gation business, presented with polyneuropathy, optic neuropathy, and cerebellar sign, and serially sampled blood, urine and cerebrospinal fluid showed significant elevation of methyl bromide concentration. Regular education to workers and strict adherence to the safety precautions are needed to avoid the risk of toxicity associated with methyl bromide fumigation.

Keyword

Methyl bromide; Polyneuropathy; Cerebellar ataxia

MeSH Terms

Edible Grain
Cerebellar Ataxia*
Cerebrospinal Fluid
Commerce
Education
Fumigation
Humans
Middle Aged
Optic Nerve Diseases*
Poisoning*
Polyneuropathies*
Soil
Soil
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