J Korean Neurol Assoc.  2000 May;18(3):372-374.

A Case of Numb-Chin Syndrome Assoicated with Hodgkin's Disease

Affiliations
  • 1Department of Neurology, Chonbuk National University Medical School.
  • 2Department of Internal Medicine, Chonbuk National University Medical School.
  • 3Department of Radiology, Chonbuk National University Medical School.

Abstract

The numb chin syndrome (NCS) is characterized by chin or lower lip numbness restricted to the distribution of the mental nerve (the distal trigeminal nerve). The authors report a patient whose initial symptom of tumor recurrence was unilateral numbness of the chin. A 65-year-old male was admitted because of paresthesia around the left chin and left lower lip. Neurologic examination revealed hypesthesia on the left side of chin, lower lip and buccal mucous mem-brane. Bone scan (Tc-99m MDP) showed focal hot uptakes on the left mandible and left first rib. Brain CT with bone window setting showed a focal osteolytic lesion in the bone marrow of the left mandibular canal without destruction of bone cortex. Both coronal T1 weighted image and axial T2 weighted image showed focal low signal intensities on the left ramus. The pathophysiologic mechanism could be understood by identification of the pathologic focus.

Keyword

Numb chin syndrome; Hodgkin's disease; Pathophysiologic mechanism

MeSH Terms

Aged
Bone Marrow
Brain
Chin
Hodgkin Disease*
Humans
Hypesthesia
Lip
Male
Mandible
Neurologic Examination
Paresthesia
Recurrence
Ribs
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