J Korean Neuropsychiatr Assoc.
2003 Mar;42(2):277-279.
Association of Low dose Trazodone Treatment with Aggravated Angle-Closure Glaucoma
- Affiliations
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- 1Department of Psychiatry, Kangnam St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract
- Trazodone has favorable pharmacological profiles with a few anticholinergic effects and cardiac conduction abnormailties. Thus it is more acceptable in geriatric population than tricyclic antidepressant (TCA) especially in patients with combined medical conditions, although attention should be paid to monitor its well-known side effects, orthostatic hypotension and priapism. Unlike expected favorable profiles, we had experienced a case of increased intraocular pressure (IOP) shortly after lowdose trazodone treatment in a known-glaucoma patient.