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Update on the Impact, Diagnosis and Management of Cardiovascular Autonomic Neuropathy in Diabetes: What Is Defined, What Is New, and What Is Unmet

Spallone V

The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase due to the diabetes epidemic and its early and widespread appearance. CAN has a definite prognostic role for...
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A Prospective, Multicenter, Open-Label Study of Dose Escalation Therapy in Male Patients With Nocturia Refractory to 0.2-mg Tamsulosin Monotherapy

Yu HS, Lee JW, Yu J, Cho MC, Cho SY

PURPOSE: To investigate the efficacy and safety of 0.4 mg of tamsulosin in patients with nocturia not responding to 0.2 mg. METHODS: Patients with intractable nocturia after treatment with 0.2 mg...
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Ideal Target Blood Pressure in Hypertension

Park S

In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive blood pressure (BP) lowering was associated with significant reduction in composite cardiovascular (CV) outcomes in hypertension. Subsequently, several meta-analyses have corroborated...
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Orthostatic hypotension with meningoencephalitis involving the rostral ventrolateral medulla

Jung YI, Sunwoo MK, Lee HJ, Seo JH, Kim J

Orthostatic hypotension (OH) is commonly associated with autonomic failure in the peripheral nervous system. Less often it is related to central lesions in brainstem and cerebellum. We describe a patient...
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Etiology and Clinical Characteristics of Pediatric Dizziness

Lee HM, Park J, Lee B, Lee KH, Park SK, Chang J

BACKGROUND AND OBJECTIVES: Dizziness is not uncommon in children. The etiology of dizziness varies according to different studies due to different methods of examination or characteristics of the dizziness center....
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Diagnosis and Management of Diabetic Autonomic Neuropathy

Kim CH

Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes, although it is often overlooked. Abnormal autonomic function tests are often found in peoples with diabetic peripheral neuropathy....
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Patterns of Orthostatic Blood Pressure Changes in Patients with Orthostatic Hypotension

Seok HY, Kim YH, Kim H, Kim BJ

BACKGROUND AND PURPOSE: The objective of this study was to determine the patterns of blood pressure (BP) changes during the head-up tilt (HUT) test, particularly in terms of its clinical...
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2018 KHRS guideline for the evaluation and management of syncope: Part 2

Kim YR, Chun KJ, Kim JS, Mun HS, Park J, Seo DW, Song MK, Ahn J, Yoon H, Lee DI, Lee YS, Cha MJ, Bae EJ, Kim DH

The general concept and initial approach to syncope patients has been mentioned in the general sections. This special sections have been described the characteristics, diagnosis, and treatment with patient education...
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Autonomic Dysfunction in Dizziness Clinic

Cho EB, Park KJ

Orthostatic dizziness is a common type of dizziness. In general, orthostatic dizziness is provoked by standing or tilting, and subsided by supine position. The patient with orthostatic intolerance complains multiple...
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Target Blood Pressure in Patients with Diabetes

Kang TS, Park S

The recently published 2017 American College of Cardiology (ACC)/American Heart Association (AHA)/American Academy of Physician Assistants/Association of Black Cardiologists/American College of Preventive Medicine/American Geriatrics Society/American Pharmacists Association/American Society of Hypertension...
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Classification of Chronic Dizziness in Elderly People and Relation with Falls

Yang DS, Lee DY, Oh SY, Park JY

OBJECTIVES: Fall is a major cause of morbidity and mortality among older adults. Falls result from many various causes, and dizziness is important risk for falls, especially in the elderly....
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Evaluation of Adrenergic Function: Tilt-Table and Valsalva Test

Lee H, Kim HA

Orthostatic dizziness is a common dizziness syndrome characterized by nonvertiginous lightheadedness when patients rise to stand from a sitting or supine position. Orthostatic dizziness is commonly believed to derive from...
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Orthostatic Hypotension and Cognitive Function in Parkinson's Disease

Kim S, Lee J, Oh E, Sohn EH, Lee AY

BACKGROUND: Although orthostatic hypotension (OH) and cognitive impairment (CI) are common non-motor symptoms of Parkinson's disease (PD), the relationship between OH and CI remains to be clarified. This study was...
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Pitfalls in the Diagnosis of Vertigo

Kim HA, Lee H

Vertigo/dizziness is a common complaint in patients who are seeking a primary health clinic. Vertigo is traditionally attributed to damage of the vestibular system. Many peripheral and central vestibular disorders...
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Validation of the Korean Version of the Scales for Outcomes in Parkinson's Disease-Sleep

Sung YH, Kim HJ, Koh SB, Kim JS, Kim SJ, Cheon SM, Cho JW, Kim YJ, Ma HI, Park MY, Baik JS, Lee PH, Chung SJ, Kim JM, Song IU, Kim HJ, Kim JY, Kwon DY, Lee JH, Lee JY, Kim JS, Yun JY, Hong JY, Kim MJ, Youn J, Kim JS, Oh ES, Yang HJ, Yoon WT, You S, Kwon KY, Park HE, Lee SY, Kim Y, Kim HT, Ahn TB

BACKGROUND: Sleep problems commonly occur in patients with Parkinson's disease (PD), and are associated with a lower quality of life. The aim of the current study was to translate the...
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Treatment of Neurogenic Orthostatic Hypotension

Byun JI, Kim SB

Orthostatic hypotension (OH) is a common feature of sympathetic autonomic dysfunction and can lead to lightheadedness, weakness, dizziness, and syncope. It is defined as decrease in systolic blood pressure of...
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Orthostatic Hypotension and Postural Orthostatic Tachycardia Syndrome in Children: Comparison of Clinical Features and Neurophysiology Test

Kim YK, Park JH, Choi HJ, Kim JS

PURPOSE: The clinical characteristics and neuropsychological tests of orthostatic hypotension (OH) and postural orthostatic tachycardia syndrome (POTS) in children were compared. METHODS: From August 2011 to April 2015, we enrolled patients...
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Syndromes of Orthostatic Intolerance: Pathophysiology and Diagnosis

Woo HO, Yeom JS

Orthostasis means standing upright. Thus, orthostatic intolerance (OI) can be simply defined as “the development of symptoms during upright standing, that are relieved by recumbency.” However, OI might be a...
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Hypothermia Presenting in Wernicke Encephalopathy: A Case Report

Hong SH, Oh JS, Lee CH, Oh JH

Wernicke encephalopathy (WE) is a neurologic disorder characterized by clinical symptoms, such as nystagmus, ataxia, and mental confusion. Hypothermia in patients with WE is a rare complication, and its pathogenic...
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Application of Near-Infrared Spectroscopy in Neurological Disorders: Especially in Orthostatic Intolerance

Kim YH, Paik SH, V ZP, Seok HY, Jeon NJ, Kim BM, Kim BJ

Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS...
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