J Korean Ophthalmol Soc.  2008 Oct;49(10):1671-1675.

Solitary Kaposi's Sarcoma of the Lower Lid in an HIV-Negative Patient

• Chung HJ
• La TY

Abstract

PURPOSE
To report a case of solitary Kaposi's sarcoma (KS) of eyelid in an HIV-negative patient, which has not yet been reported in domestics.
CASE SUMMARY
A 76-year-old woman was seen at our clinic with a purplish nodular mass on her left lower lid that had grown up for 4 months prior. There were no abnormal findings in the body except eyelid. In the routine laboratory examinations, the result of HIV test was negative. The lesion was completely excised and the eyelid was reconstructed by semicircular rotational flap procedure. The histopathologic examination showed spindle cells of mild atypism, intermixed with slit-like vascular spaces and red blood cell extravastaion. These findings coincided with KS and polymerase chain reaction was positive for human herpes virus-8. During 10 months follow up, there was no evidence of tumor recurrence and systemic abnormalities.
CONCLUSIONS
We experienced that Kaposi's sarcoma can occur solitarily in the eyelid of HIV-negative patient and favorable prognosis can be obtained by only surgical resection.

Keyword

Eyelid; HIV-negative patient; Kaposi's sarcoma

MeSH Terms

Aged
Erythrocytes
Eyelids
Female
Follow-Up Studies
HIV
Humans
Polymerase Chain Reaction
Prognosis
Recurrence
Sarcoma, Kaposi

Figure

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  Figure 1. Photograph shows an indurated violaceous Broad- based mass on the left lower lid.

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  Figure 2. (A) Immediate postoperative photograph after performing semicircular flap surgery to reconstruct tumor excision site of the lower lid (postoperative 1 day). (B) Photograph shows well reconstructed lower lid (posto-perative 2 months).

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  Figure 3. (A) A sarcomatoid lesion is formed by spindle cells and clusters of many small capillaries (hematoxylin-eosin, ×100). (B) The vascular neoplasm is consisted of immature spindle cells with mild atypism and plump endothelial cells that line slit-like vascular channels. Extravasated red blood cells in slit-like channels and hyperchromatic nuclei in spindle cells were also observed (hematoxylin-eosin, ×400).

Reference

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