J Korean Ophthalmol Soc.  2007 Nov;48(11):1479-1486.

Changes in Anterior Chamber Depth and Refraction after Accommodative Intraocular Lens Implantation

• Kim JH
• Park CS
• Chung ES
• Chung TY

Abstract

PURPOSE: To evaluate the change in anterior chamber depth and refraction after AT-45 implantation
METHODS
Twenty-two eyes from 22 patients were enrolled in this prospective study. After phacoemulsification, AT-45 (11 eyes) and SA60AT (11 eyes) were implanted. Clinical data included anterior chamber depth and refractive error at 1 week, 1 month, 2 months and 6 months postoperatively. The correlation between anterior chamber depth change and spherical equivalent change was also evaluated.
RESULTS
In the AT-45 implanted group, the mean anterior chamber depth was 4.56+/-0.59 mm at 1 week postoperative, 4.70+/-0.69 mm at 1 month postoperative, 4.78+/-0.71 mm at 2 months postoperative and 4.76+/-0.69 mm at 6 months postoperative. The mean spherical equivalent was -0.53+/-0.48D, -0.37+/-0.42D, -0.27+/-0.47D, and -0.33+/-0.44D respectively. When analyzed using the Mann-Whitney U test, p-values of anterior chamber depth differences between the 2 groups were P=0.52 at 1 week to 1 month, P=0.32 at 1 month to 2 months, P=0.89 at 2 months to 6 months, and P=0.02 at 1 week to 6 months, showing a deeper anterior chamber in the AT-45 implanted group. P-values (Mann-Whitney U test) of spherical equivalent differences between the 2 groups were P=0.33, P=0.56, P=0.94, and P=0.19, respectively, showing more hyperopic change in the AT-45 implanted group. The correlation between anterior chamber depth change and spherical equivalent change in the AT-45 implanted group at 1 week to 6 months was not statistically significant (Spearman correlation analysis, P=0.223).
CONCLUSIONS
Anterior chamber depth deepening and associated hyperopic refractive change were observed after AT-45 implantation, especially at 1 month after the surgery.

Keyword

Accommodative IOL; Anterior chamber depth; AT-45; Crystalens; Refraction

MeSH Terms

Anterior Chamber*
Humans
Lens Implantation, Intraocular*
Lenses, Intraocular*
Phacoemulsification
Prospective Studies
Refractive Errors

Figure

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  Figure 1. Changes in mean anterior chamber depth (ACD) after AT-45 (n=11) and SA60AT (n=11) implantation, according to the follow-up period.

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  Figure 2. Mean anterior chamber depth (ACD) difference in AT-45 group (n=11) and SA60AT group (n=11), according to the follow-up period. Positive value represents deepening of the anterior chamber, whereas negative value represents shallowing of the anterior chamber (* : Mann-Whitney U test, W: week, M: month).

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  Figure 3. Mean spherical equivalent (SE) change after AT-45 (n=11) and SA60AT (n=11) implantation, according to the follow-up period.

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  Figure 4. Mean spherical equivalent (SE) difference in AT-45 group (n=11) and SA60AT group (n=11), according to the follow-up period. Positive value represents hyperopic change, whereas negative value represents myopic change in spherical equivalent (* : Mann-Whitney U test, W: week, M: month).

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  Figure 5. Anterior chamber depth (ACD) and spherical equivalent (SE) change in AT-45 implanted group. Correlation between ACD change and SE change between 1 week and 6 months was not statistically significant (Spearman correlation analysis, P=0.223).

Reference

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