J Korean Ophthalmol Soc.  2006 Apr;47(4):667-671.

A Case of Central Retinal Artery Occlusion after Intravitreal Triamcinolone Acetonide Injection for Diabetic Macular Edema in Non-Proliferative Diabetic Retinopathy

• Shin JH
• Kim DK
• Yu SY
• Kwak HW

Abstract

PURPOSE: We report a case of central retinal artery occlusion after two intravitreal injections of triamcinolone acetonide for diabetic macular edema due to non-proliferative diabetic retinopathy.
METHODS
A forty-six year old man with a ten-year history of DM visited our clinic because of diminished vision in his right eye (0.02). He received intravitreal triamcinolone acetonide for diabetic macular edema due to NPDR. After injection, he showed recovery of visual acuity (0.9) and decrease of macular edema. After two months, he received a second intravitreal triamcinolone acetonide injection because his visual acuity had diminished during the two-month period. Fifteen days after the second injection, visual acuity of his right eye suddenly diminished to no light perception. At this time, we performed fundus photograph, fluorescein angiography, and optical coherence tomography.
RESULTS
From the fundus exam, we diagnosed the patient with CRAO and prescribed an antithrombotic agent. Five month after the occlusion, visual acuity of the right eye improved 0.3, but generalized sclerosis of retinal vessels was present. Eight months after the occlusion, however he developed neovascular glaucoma and visual acuity of the right eye fell to the light perception negative range.
CONCLUSIONS
We experienced a case of central retinal artery occlusion after intravitreal triamcinolone acetonide injection. Therefore, possible vascular complications should be considered following this type of injection.

Keyword

Central retinal artery occlusion; Diabetic macular edema; Interactional triamcinolone acetified injection; Non-proliferative diabetic retinopathy

MeSH Terms

Diabetic Retinopathy*
Fluorescein Angiography
Glaucoma, Neovascular
Humans
Intravitreal Injections
Macular Edema*
Retinal Artery Occlusion*
Retinal Artery*
Retinal Vessels
Sclerosis
Tomography, Optical Coherence
Triamcinolone Acetonide*
Triamcinolone*
Vision, Low
Visual Acuity
Triamcinolone
Triamcinolone Acetonide